162553-81-3

Upstream product

• 87-72-9 D-Xylose 
• 100-52-7 benzaldehyde 
• 90581-32-1 α-D-xylofurano<1,2,d>oxazolidin-2'-one 

Downstream Products

• 176965-50-7 (3aS,4aR,7S,8aS,8bR)-3-Butyryl-7-phenyl-hexahydro-[1,3]dioxino[4',5':4,5]furo[2,3-d]oxazol-2-one 
• 191287-15-7 (3aS,4aR,7S,8aS,8bR)-3-Acetyl-7-phenyl-hexahydro-[1,3]dioxino[4',5':4,5]furo[2,3-d]oxazol-2-one 

Relevant academic research and scientific papers

Resolution of Racemic Carboxylic and Sulfonic Acids via D-Xylose Derived New Cyclic Carbamate Reagents (Oxazolidin-2-ones)

Two new chiral oxazolidin-2-ones have been easily prepared from D-xylose and studied as chiral derivatizing agents (CDA's) for the resolution of racemic carboxylic and sulfonic acids.The resultant diastereomers are readily separated by chromatographic methods and easily hydrolyzed to isolate the resolved materials in high optical purities and to return the CDA's for reuse.

D-xylose derived oxazolidin-2-ones as chiral auxiliaries in stereoselective aldol reactions

Chiral N-acylated oxazolidin-2-one derivatives from D-xylose have been shown to undergo diastereoselective aldol reactions via their lithium imide enolates to afford β-hydroxylated products. Aliphatic substrates and aldehydes were shown to yield 'non-Evan