16256-41-0

Basic information

• Product Name: 7,14-Diazadispiro[5.1.5.2]pentadecan-15-one
• Synonyms: 2,5-Bis(spirocyclohexyl)imidazolidin-4-one;7,14-Diaza-15-oxodispiro[5.1.5.2]pentadecane; Cyclohexane-1-spiro-2'-(4'-oxoimidazolidine)-5'-spiro-1'-cyclohexane;Cyclohexane-1-spiro-2'-(4'-oxoimidazolidine)-5'-spiro-1''-cyclohexane; NSC643429; NSC 79632
• CAS NO: 16256-41-0
• Molecular Formula: C₁₃H₂₂N₂O
• Molecular Weight: 222.3266
• Mol File: 16256-41-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 431.3°C at 760 mmHg
• Flash Point: 175.8°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 1.22E-07mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: 7,14-Diazadispiro[5.1.5.2]pentadecan-15-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7,14-Diazadispiro[5.1.5.2]pentadecan-15-one(16256-41-0)
• EPA Substance Registry System: 7,14-Diazadispiro[5.1.5.2]pentadecan-15-one(16256-41-0)

Safety Data

• Hazardous Substances Data: 16256-41-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H22N2O/c16-11-12(7-3-1-4-8-12)15-13(14-11)9-5-2-6-10-13/h15H,1-10H2,(H,14,16)

Upstream product

• 113-00-8 guanidine nitrate 
• 5496-10-6 1-amino-1-cyanocyclohexane 

Downstream Products

• 57231-99-9 14-p-tolylcarbamoyl-7,14-diazadispiro[5.1.5.2]pentadecan-15-one 
• 57231-95-5 15-oxo-7,14-diaza-dispiro[5.1.5.2]pentadecane-14-carboxylic acid cyclohexylamide 
• 57232-00-5 14-p-chlorophenylcarbamoyl-7,14-diazadispiro[5.1.5.2]pentadecan-15-one 
• 57232-02-7 15-thioxo-7,14-diaza-dispiro[5.1.5.2]pentadecane-14-carboxylic acid anilide 
• 57231-91-1 15-oxo-7,14-diaza-dispiro[5.1.5.2]pentadecane-14-carboxylic acid anilide 
• 40003-74-5 14-benzyl-7,14-diaza-dispiro[5.1.5.2]pentadecan-15-one 

Relevant articles and documents

Reactions of Guanidine and Urea with Aminonitriles

The aminonitriles 3a-f react with guanidine in DMF to yield the 5,5- resp. 5-substituted imidazolidine-2,4-diimines 2a-d resp. 2f, whereas 2e could not be isolated. 7,14-diazadispiro-pentadecan-15-on (7), 4-imino-1,3-diazaspirodecan-2-one (8a) and the 2,4-diaminotriazine (9) were isolated as byproducts. 1-Aminocyclohexancarbonitrile (3a) reacts with urea to the 4-imino-1,3-diazaspirodecan-2-one (8a); 8a can be prepared from (1-cyancyclohexyl)urea (11a) as well.The structures of the new compounds are proved by NMR-, IR- and mass spectra and the mechanism of the reaction is discussed. - Keywords: Aminonitriles, reaction with guanidine resp. urea; 1,3-Diazaspirodecan-2-one, 4-imino; 1,3-Diazaspirononan-resp. decan-2,4-diimimne; Guanidine, reactions with aminonitriles; Imidazolidin-2,4-diimines, 5-substituted; Urea, reactions with aminonitriles