16257-76-4 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
Pyrrolidine is a heterocyclic amine and serves as the core structure for this compound.
Explanation
DPP-IV is an enzyme involved in glucose metabolism, and this compound has been identified as a potential inhibitor, which could be useful in treating type 2 diabetes.
Explanation
The compound's ability to inhibit DPP-IV and its chemical structure make it a promising candidate for further research in the treatment of these conditions.
Explanation
The compound's potential therapeutic applications and chemical properties make it a subject of interest for researchers in the field of medicinal chemistry.
Explanation
The specific arrangement of these functional groups in the molecule contributes to its unique properties and potential applications.
Derivative of pyrrolidine
Yes
Sulphonate group
Attached to the benzene ring
Potential inhibitor
Dipeptidyl peptidase-IV (DPP-IV)
Applications
Type 2 diabetes, cardiovascular diseases, and cancer treatment
Field of interest
Medicinal chemistry
Chemical structure
Contains a benzene ring, a pyrrolidine ring, a hydroxyl group, a carboxylic acid group, and a sulphonate group
Check Digit Verification of cas no
The CAS Registry Mumber 16257-76-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,5 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 16257-76:
(7*1)+(6*6)+(5*2)+(4*5)+(3*7)+(2*7)+(1*6)=114
114 % 10 = 4
So 16257-76-4 is a valid CAS Registry Number.
16257-76-4Relevant articles and documents
Studies on the synthesis of cis-4-hydroxy-L-proline
Smith, Jessica A.,Savage, G. Paul,Hutt, Oliver E.
, p. 1509 - 1514 (2011)
A high yielding practical three-step procedure, which relies on an extractive work-up procedure, has been developed to convert N-phenylsulfonyl- trans-4-hydroxy-l-proline to N-phenylsulfonyl-cis-4-hydroxy-l-proline methyl ester in 82% yield over three steps.
HIV protease inhibitors based on amino acid derivatives
-
, (2008/06/13)
A compound selected from the group consisting of a compound of formula I 1a compound of formula II 2and when the compound of formula I and II comprises an amino group pharmaceutically acceptable ammonium salts thereof, wherein R1, R2, Cx, n, R3, R4, R5, Y are as defined in the specification.
