162648-31-9Relevant academic research and scientific papers
Decarboxylative fluorination of aliphatic carboxylic acids via photoredox catalysis
Ventre, Sandrine,Petronijevic, Filip R.,Macmillan, David W. C.
supporting information, p. 5654 - 5657 (2015/05/20)
The direct conversion of aliphatic carboxylic acids to the corresponding alkyl fluorides has been achieved via visible light-promoted photoredox catalysis. This operationally simple, redox-neutral fluorination method is amenable to a wide variety of carboxylic acids. Photon-induced oxidation of carboxylates leads to the formation of carboxyl radicals, which upon rapid CO2-extrusion and F? transfer from a fluorinating reagent yield the desired fluoroalkanes with high efficiency. Experimental evidence indicates that an oxidative quenching pathway is operable in this broadly applicable fluorination protocol.
PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE
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, (2012/06/18)
Provided is a compound represented by the Formula (I) having a HER2 inhibitory action or a pharmacologically acceptable salt thereof, wherein T1 is a phenyl group, an indazolyl group, or a benzofuryl group, n is an integer of 0 to 3, R1 /
Hindered esters of rapamycin
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, (2008/06/13)
A compound of the structure STR1 wherein R and R1 are each, independently, STR2 or hydrogen; R2 and R3 are each, independently, alkyl, arylalkyl, or R2 and R3 may be taken together to form a cycloalky
