163271-08-7

Basic information

• Product Name: tert-Butyl (4-methylpiperidin-4-yl)carbamate
• Synonyms: 4-Methylpiperidin-4-yl)carbami;(4-Methylpiperidin-4-yl)carbamic acid tert-butyl ester;tert-Butyl (4-methyl-4-piperidinyl)carbamate;(4-Methylpiperidin-4-yl)carbamic acid 1,1-dimethylethyl ester;tert-Butyl (4-methylpiperidin-4-yl)carbamate;4-(Boc-amino)-4-methylpip...;4-(Boc-aMino)-4-Methylpiperidine;tert-Butyl N-(4-Methyl-4-piperidyl)carbaMate
• CAS NO: 163271-08-7
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.3
• Product Categories: API intermediates
• Mol File: 163271-08-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 308 °C
• Flash Point: 140 °C
• Appearance: White to off-white powder
• Density: 1.01
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.481
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 12.75±0.20(Predicted)
• CAS DataBase Reference: tert-Butyl (4-methylpiperidin-4-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl (4-methylpiperidin-4-yl)carbamate(163271-08-7)
• EPA Substance Registry System: tert-Butyl (4-methylpiperidin-4-yl)carbamate(163271-08-7)

Safety Data

• Hazardous Substances Data: 163271-08-7(Hazardous Substances Data)

Usage

Description

Tert-Butyl (4-methylpiperidin-4-yl)carbamate, with the molecular formula C11H23N3O2, is a versatile chemical compound that serves as a crucial precursor in the synthesis of pharmaceuticals and agrochemicals. It is recognized for its role as a protecting group for amines in organic synthesis, and its potential as a drug delivery system and treatment for certain diseases. Its low toxicity and stable properties make it a valuable component across various industries.

Uses

Used in Pharmaceutical and Agrochemical Industries:
Tert-Butyl (4-methylpiperidin-4-yl)carbamate is used as a precursor in the synthesis of various pharmaceuticals and agrochemicals for its ability to facilitate the creation of complex molecules with desired properties.
Used as a Protecting Group in Organic Synthesis:
In organic synthesis, tert-Butyl (4-methylpiperidin-4-yl)carbamate is utilized as a protecting group for amines, allowing chemists to temporarily mask the reactivity of amine groups during reactions, ensuring selective reactions at other sites on the molecule.
Used in Drug Delivery Systems:
Tert-Butyl (4-methylpiperidin-4-yl)carbamate has been studied for its potential as a drug delivery system, where it can be used to encapsulate and release therapeutic agents in a controlled manner, improving the efficacy and safety of drug administration.
Used in the Development of Potential Disease Treatments:
Research is ongoing into the use of tert-Butyl (4-methylpiperidin-4-yl)carbamate as a potential treatment for certain diseases, leveraging its chemical properties to target specific biological pathways or mechanisms.
Used in Various Industries:
Due to its low toxicity and relatively stable nature, tert-Butyl (4-methylpiperidin-4-yl)carbamate is employed in a range of industries beyond pharmaceuticals and agrochemicals, including materials science and chemical manufacturing, for its ability to contribute to the development of new products and processes.

InChI:InChI=1/C11H22N2O2/c1-10(2,3)15-9(14)13-11(4)5-7-12-8-6-11/h12H,5-8H2,1-4H3,(H,13,14)

Upstream product

• 162648-31-9 1-benzoyl-4-methylpiperidine-4-carboxylic acid 
• 1262787-56-3 (1-benzoyl-4-methylpiperidin-4-yl)carbamic acid tert-butyl ester 
• 162648-30-8 1-benzoyl-4-methylpiperidine-4-carboxylic acid ethyl ester 
• 136081-74-8 ethyl 1-benzoyl-4-piperidine-carboxylate 
• 1126-09-6 4-carbethoxypiperidine 
• 67-56-1 methanol 
• 3934-20-1 2,6-Dichloropyrimidine 
• 163271-07-6 tert-butyl 1-benzyl-4-methylpiperidin-4-ylcarbamate 
• 75-09-2 dichloromethane 

Downstream Products

• 1801747-42-1 6-(4-amino-4-methylpiperidine-1-yl)-3-(2,3-dichlorophenyl)pyrazine-2-amine 
• 1874276-76-2 3-amino-N-(3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl)-6-(3-(trifluoromethyl)pyridin-2-yl)pyrazine-2-carboxamide 
• 1801747-11-4 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine hydrochloride 
• 1464156-26-0 tert-butyl 1-(4-(3-(4-cyanophenyl)-7-methylimidazo[1,2-a]pyridin-6-yl)benzoyl)-4-methylpiperidin-4-ylcarbamate 
• 1464159-05-4 tert-butyl 1-(4-(3-(4-cyanophenyl)pyrazolo[1,5-a]pyrimidin-5-yl)benzoyl)-4-methylpiperidin-4-ylcarbamate 
• 1464158-68-6 tert-butyl 1-(4-(3-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)benzoyl)-4-methylpiperidin-4-ylcarbamate 

Relevant articles and documents

PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE

Provided is a compound represented by the Formula (I) having a HER2 inhibitory action or a pharmacologically acceptable salt thereof, wherein T1 is a phenyl group, an indazolyl group, or a benzofuryl group, n is an integer of 0 to 3, R1 /

1-HALOPYRIDIN-4-AMINO-4-ALKYLPIPERIDINES

The present invention relates to novel heteroarylpiperidines of formula (I): STR1 in which Hal is a halogen atom, Alk is a C 1-C. sub.4 alkyl group and X, Y and Z are each--CH= and their salts, to a process for their preparation and to their use as drugs active as 5-HT. sub.3 agonists.