162685-91-8Relevant academic research and scientific papers
Synthesis of (S)-(-)-Cucurbitine and Conformation of Its Homopeptides
Yamaberi, Yuto,Eto, Ryo,Umeno, Tomohiro,Kato, Takuma,Doi, Mitsunobu,Yokoo, Hidetomo,Oba, Makoto,Tanaka, Masakazu
, p. 4358 - 4362 (2021)
A chiral cyclic α,α-disubstituted α-amino acid, (S)-(-)-cucurbitine, which has a pyrrolidine ring with a chiral center at the α-position, was synthesized, and its homopeptides were prepared. (S)-(-)-Cucurbitine homopeptides with a Boc-protecting group formed helical structures with slight control of the helical screw sense to the left-handed form. The state of the pyrrolidine ring in (S)-(-)-cucurbitine was important for the control of the helical structures and helical screw sense of its homopeptides.
8-methoxy-quinolonecarboxylic acid derivatives
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, (2008/06/13)
8-Methoxy-quinolonecarboxylic acid derivatives of the formula STR1 wherein R1 is a hydrogen atom, a lower alkyl, a phenylalkyl or an ester residue hydrolyzable in the living body, R2 is a hydrogen atom or methyl and n is an integer o
