16269-13-9Relevant articles and documents
SYNTHESIS AND ANTIVIRAL ACTIVITY OF THE HYDROCHLORIDES OF ALICYCLIC MONO- AND DIAMINES
Novakov, I. A.,Kulev, I. A.,Radchenko, S. S.,Birznieks, K. A.,Boreko, E. I.,et al.
, p. 287 - 291 (1987)
-
Adamantylation of carbonitriles with 1,3-dehydroadamantane and its homologs
Mokhov,Butov
, p. 1279 - 1282 (2014)
1,3-Dehydroadamantane and its methyl-substituted homologs react with carbonitriles at the α-carbon atom of the latter to give the corresponding α-adamantyl carbonitriles. This reaction provide a convenient one-step procedure for selective synthesis of branched nitriles which are difficult to obtain by traditional procedures.
Conversion of 3,3,3-Trisubstituted Prop-1-ynes with tert-Butylhydrazine into 3,3,3-Trisubstituted Propionitriles Catalyzed by TpRh(C2H4)2/P(2-furyl)3
Fukumoto, Yoshiya,Tamura, Yuto,Iyori, Yasuaki,Chatani, Naoto
, p. 3161 - 3167 (2016/05/19)
The combination of TpRh(C2H4)2 (Tp = tris(pyrazol-1-yl)borate) and P(2-furyl)3 catalyzes the reaction of tertiary alkyl-substituted alkynes with tert-butylhydrazine, leading to the formation of 3,3,3-trisubstituted propionitrile derivatives. This reaction system is applicable to 1,1-disubstituted propargyl alcohols and amines to afford the corresponding β-cyanohydrins and β-amino nitriles, respectively. The catalytic cycle involves the formation of a vinylidenerhodium complex as a key intermediate.
