162698-26-2Relevant academic research and scientific papers
Carbonyl azetidine substituted naphthalimide fluorescent dye as well as synthesis method and application thereof
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Paragraph 0073-0077, (2021/06/13)
The invention provides a novel carbonyl azetidine substituted naphthalimide fluorescent dye as well as synthesis and application thereof. The dye takes 1, 8-naphthalimide as a fluorophore parent, and the fourth site of the 1, 8-naphthalimide is covalently connected with carbonyl azetidine. The novel fluorescent dye has excellent fluorescence intensity and light stability, so that the novel fluorescent dye has wide application prospects in the fields of fluorescence detection, fluorescence imaging and the like, especially in the emerging fields of single molecule detection, super-resolution fluorescence imaging and the like. R1 is H, C1-4 alkyl and aryl, R2 is shown in the specification, and in R2, X1 is H, C1-2 alkyl, X2 is C1-2 alkyl or shown in the specification, X3 is C1-2 alkyl or shown in the specification, and X4 is C1-2 alkyl.
Carbonyl azetidine substituted coumarin fluorescent dye as well as synthesis method and application thereof
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Paragraph 0051-0055, (2021/06/12)
The invention provides a novel carbonyl azetidine substituted coumarin fluorescent dye as well as synthesis and application thereof. The structural innovation of the dye is that carbonyl azetidine is covalently linked to the No.7 site of a coumarin parent. The novel fluorescent dye has excellent fluorescence intensity and light stability, so that the novel fluorescent dye has wide application prospects in the fields of fluorescence detection, fluorescence imaging and the like, especially in the emerging fields of single molecule detection, super-resolution fluorescence imaging and the like. R1 is C1-4 alkyl, and R2 is shown in the specification, X1 is H or C1-2 alkyl, X2 is C1-2 alkyl or shown in the specification, X3 is C1-2 alkyl or shown in the specification, and X4 is C1-2 alkyl.
Carbonyl azetidine substituted NBD fluorescent dye as well as synthesis method and application thereof
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Paragraph 0047-0051, (2021/06/12)
The invention provides a novel carbonyl azetidine substituted NBD fluorescent dye as well as synthesis and application thereof. The structure of the dye is characterized in that carbonyl azetidine is covalently connected to the fourth site of a 4-chloro-7-nitrobenzene-2-oxa-1, 3-diazole (NBD) parent. The novel fluorescent dye has excellent fluorescence intensity and light stability, so that the novel fluorescent dye has wide application prospects in the fields of fluorescence detection, fluorescence imaging and the like, especially in the emerging fields of single molecule detection, super-resolution fluorescence imaging and the like. R1 is as described in the specification, X1 is H or C1-2 alkyl, X2 is C1-2 alkyl or as described in the specification, x3 is C1-2 alkyl or as described in the specification, and X4 is C1-2 alkyl.
Neurotrophic 2-azetidinecarboxylic acid derivatives, and related compositions and methods
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, (2008/06/13)
This invention provides compounds having the following general structure: This invention also provides pharmaceutical compositions comprising same and methods of using these compositions to treat and prevent disorders characterized by neuronal damage.
