162751-93-1

Basic information

• Product Name: 5-fluoro-2-(hydroxyimino)-2,3-dihydro-1H-inden-1-one
• Synonyms: 5-fluoro-2-(hydroxyimino)-2,3-dihydro-1H-inden-1-one;5-FLUORO-2-OXIMINO-1-INDANONE
• CAS NO: 162751-93-1
• Molecular Formula: C9H6FNO2
• Molecular Weight: 179.1478432
• Mol File: 162751-93-1.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-fluoro-2-(hydroxyimino)-2,3-dihydro-1H-inden-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-2-(hydroxyimino)-2,3-dihydro-1H-inden-1-one(162751-93-1)
• EPA Substance Registry System: 5-fluoro-2-(hydroxyimino)-2,3-dihydro-1H-inden-1-one(162751-93-1)

Safety Data

• Hazardous Substances Data: 162751-93-1(Hazardous Substances Data)

Usage

General Description

5-Fluoro-2-(hydroxyimino)-2,3-dihydro-1H-inden-1-one, also known as Tolfenamic acid, is a nonsteroidal anti-inflammatory drug (NSAID) that is used for its analgesic and anti-inflammatory properties. It works by inhibiting the production of prostaglandins, which are responsible for inflammation and pain. Tolfenamic acid has been shown to be effective in treating various conditions, including arthritis, menstrual pain, and migraines. It is available in both oral and topical forms and is generally well-tolerated, with common side effects including gastrointestinal upset and dizziness. Tolfenamic acid is a promising option for pain management and inflammation control due to its potent and targeted mechanism of action.

Upstream product

• 700-84-5 5-fluoro-1-indanone 
• 109-95-5 ethyl nitrite 
• 110-46-3 isopentyl nitrite 

Downstream Products

• 1041423-28-2 3-chloro-6-fluoroisoquinoline 
• 2340-06-9 5-fluoro-2,3-dihydro-1H-inden-2-amine 

Relevant articles and documents

Squaramide-catalysed asymmetric Michael addition/cyclization cascade reaction of 4-arylmethylidene-2,3-dioxopyrrolidines with 2-isothiocyanato-1-indanones

A highly efficient cinchona alkaloid-derived squaramide catalysed asymmetric Michael/cyclization cascade reaction of 4-arylmethylidene-2,3-dioxopyrrolidines with 2-isothiocyanato-1-indanones was successfully developed. This protocol provides an efficient

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

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