162809-96-3

Upstream product

• 114655-02-6 2'-O-(tert-butyldimethylsilyl)paclitaxel 
• 33069-62-4 taxol 
• 162664-57-5 2'-O-TBDMS-7-O-TES-9-α-OH-9-desoxo-10-epi-paclitaxel 
• 849213-03-2 2-O-TBDMS-9-α-OH-9-desoxo-10-epi-paclitaxel 
• 162664-55-3 2'-TBS-10-deacetyl-7-TES-10α-hydroxypaclitaxel 
• 162809-97-4 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel 
• 162664-54-2 2'-O-TBDMS-7-O-TES-9,10-diketo-paclitaxel 
• 162664-56-4 2'-O-TBDMS-7-O-TES-9,10-α,α-OH-9-desoxo-10-deacetylpaclitaxel 
• 162375-26-0 2'-O-(tert-butyldimethylsilyl)-10-deacetylpaclitaxel 
• 78432-77-6 10-deacetylpaclitaxel 

Downstream Products

• 849213-09-8 9-desoxo-7,9-anisaldehyde acetal 10-epipaclitaxel 
• 849213-04-3 2'-O-TES-9-α-OH-10-epi-paclitaxel 
• 849342-14-9 C₆₂H₇₁NO₁₇ 
• 849213-10-1 7,9-anisaldehyde acetal-9-desoxo-10-epi-baccatin III 

Relevant academic research and scientific papers

Biologically Active Taxane Analogs and Methods of Treatment

The present application relates to new taxane analogs, pharmaceutical compositions comprising such analogs and methods of treating cancer comprising such compositions. The compounds according to the present application have the general formula: wherein R

9,10-alpha,alpha-OH-TAXANE ANALOGS AND METHODS FOR PRODUCTION THEREOF

The present invention relates to new taxane analogs useful for the treatment of cancer as well as methods for producing the same. The chemical compounds according to the present invention have the general Formula (I) wherein R1 and R2 are each selected fr

The chemistry of the taxane diterpene: Stereoselective reductions of taxanes

Stereoselective reductions of taxanes are detailed. Chelation- controlled reductions employing SmI2 are described for the stereoselective reduction of the 9-keto functionality of the diterpene moiety of several taxanes. In all cases the 9β-hydr

Syntheses of Novel C-9 and C-10 Modified Bioactive Taxanes

A method has been developed for the syntheses of hitherto unreported C-9 and C-10 modified taxanes.These analogs demonstrated excellent to good cytotoxicity against B 16 melanoma cells.