163083-84-9

Basic information

• Product Name: methyl 11-cyano-8-(2-naphthylmethyl)-3-phenyl-4,8-diazaundecanoate
• Synonyms: methyl 11-cyano-8-(2-naphthylmethyl)-3-phenyl-4,8-diazaundecanoate
• CAS NO: 163083-84-9
• Molecular Weight: 443.589
• Mol File: 163083-84-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 11-cyano-8-(2-naphthylmethyl)-3-phenyl-4,8-diazaundecanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 11-cyano-8-(2-naphthylmethyl)-3-phenyl-4,8-diazaundecanoate(163083-84-9)
• EPA Substance Registry System: methyl 11-cyano-8-(2-naphthylmethyl)-3-phenyl-4,8-diazaundecanoate(163083-84-9)

Safety Data

• Hazardous Substances Data: 163083-84-9(Hazardous Substances Data)

Upstream product

• 209183-09-5 t-butyl (S)-3-(benzhydrylamino)-3-phenylpropionate 
• 163083-83-8 N-(3-cyanopropyl)-N-(2-naphthylmethyl)-3-amino-1-propanol 
• 62506-88-1 (E)-N-(phenylmethylene)benzhydrylamine 
• 163083-81-6 methyl (S)-3-(benzhydrylamino)-3-phenylpropionate 
• 163083-82-7 3-((naphthalen-2-ylmethyl)amino)propan-1-ol 
• 37088-66-7 (3S)-methyl 3-amino-3-phenylpropanoate 

Downstream Products

• 163083-85-0 (S)-3-[3-(3-Cyano-propylamino)-propylamino]-3-phenyl-propionic acid methyl ester 
• 126641-91-6 (S)-4-phenyl-1,5,9-triazacyclotridecan-2-one 
• 65094-32-8 (S)-4-phenyl-9-(3-phenylprop-2-enoyl)-1,5,9-triazacyclotridecan-2-one 
• 209183-01-7 methyl 12-amino-3-phenyl-4,8-diazadodecanoate 

Relevant articles and documents

Metal-Templated Macrolactamization of Triamino and Tetramino Esters. Facile Synthesis of Macrocyclic Spermidine and Spermine Alkaloids, (S)-(+)-Dihydroperiphylline, (±)-Buchnerine, (±)-Verbacine, (±)-Verbaskine, and (±)-Verbascenine

The total synthesis of spermidine and spermine alkaloids. (S)-(+)-dihydroperiphylline (1), (±)-buchnerine (2), (±)-verbacine (3), (±)-verbaskine (4), and (±)-verbascenine (5), is described. The construction of macrocyclic lactams has been efficiently accomplished by the metal-templated cyclization of triamino esters and tetraamino esters. It was also found that the antimony(III) ethoxide is useful as an intermolecular amidation catalyst.