163129-79-1 Usage
Uses
Used in Organic Synthesis:
2-IODO-5-METHOXYPYRIDINE is used as a reactant and reagent for organic reactions due to its unique chemical properties. Its iodine and methoxy substituents make it a versatile building block for the creation of a wide range of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-IODO-5-METHOXYPYRIDINE is utilized as a key intermediate in the synthesis of various drugs and drug candidates. Its reactivity allows for the development of new therapeutic agents with potential applications in treating different medical conditions.
Used in Chemical Research:
2-IODO-5-METHOXYPYRIDINE is also employed in academic and industrial research settings as a valuable compound for exploring new reaction pathways and understanding the fundamental principles of organic chemistry. Its unique structure and reactivity make it an attractive candidate for studying various chemical transformations and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 163129-79-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,1,2 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 163129-79:
(8*1)+(7*6)+(6*3)+(5*1)+(4*2)+(3*9)+(2*7)+(1*9)=131
131 % 10 = 1
So 163129-79-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H6INO/c1-9-5-2-3-6(7)8-4-5/h2-4H,1H3
163129-79-1Relevant academic research and scientific papers
A revised synthesis of the antitumour antibiotic L-azatyrosine via 2-iodo-5-methoxypyridine
Seton, Alison W.,Stevens, Malcolm F. G.,Westwell, Andrew D.
, p. 546 - 548 (2007/10/03)
A revised synthesis of the antitumour antibiotic L-azatyrosine is reported, the main features of which are the unambiguous synthesis of the previously misinterpreted 2-iodo-5-methoxypyridine and subsequent palladium-catalysed coupling with an iodoalanine-derived zinc reagent.
New water-soluble duocarmycin derivatives: Synthesis and antitumor activity of A-ring pyrrole compounds bearing β-heteroarylacryloyl groups
Amishiro, Nobuyoshi,Nagamura, Satoru,Kobayashi, Eiji,Gomi, Katsushige,Saito, Hiromitsu
, p. 669 - 676 (2007/10/03)
A series of A-ring pyrrole compounds of duocarmycin bearing 4'-methoxy- β-heteroarylacryloyl groups were synthesized and evaluated for in vitro anticellular activity against HeLa S3 cells and in vivo antitumor activity against murine sarcoma 18
DC-89 derivatives
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, (2008/06/13)
Provided are DC-89 derivatives represented by the formula: STR1 wherein X represents Cl or Br, R represents hydrogen or COR1, and W represents STR2 and pharmaceutically acceptable salts thereof. The compounds of the present invention have excellent anti-tumor activity and are useful as anti-tumor agents.
