1632073-02-9Relevant academic research and scientific papers
Arylboration of 1-Arylalkenes by Cooperative Nickel/Copper Catalysis
Semba, Kazuhiko,Ohtagaki, Yasuhiro,Nakao, Yoshiaki
, p. 3956 - 3959 (2016)
A method for the arylboration of 1-arylalkenes with bis(pinacolato)diboron and aryl chlorides or tosylates by cooperative Ni/Cu catalysis has been developed, which affords 2-boryl-1,1-diarylalkanes in high regio- and stereoselectivity. Under the applied conditions, this method is tolerant toward various functional groups, including silyl ether, alkoxycarbonyl, and aminocarbonyl moieties.
Arylboration of alkenes by cooperative palladium/copper catalysis
Semba, Kazuhiko,Nakao, Yoshiaki
supporting information, p. 7567 - 7570 (2014/06/10)
Arylboration of vinylarenes and methyl crotonate with aryl halides and bis(pinacolato)diboron by cooperative Pd/Cu catalysis has been developed, giving 2-boryl-1,1-diarylethanes and an α-aryl-β-boryl ester in a regioselective manner. The reaction is compatible with a variety of functionalities and amenable to be scaled-up to a gram scale with no detriment to the yield. A short synthesis of the biologically active compound CDP840 was performed using the present reaction as a key step.
