163263-91-0Relevant academic research and scientific papers
INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF
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Paragraph 00441, (2018/03/09)
A class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
Influenza virus replication inhibitor and application thereof
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Paragraph 0595; 0597; 0598, (2018/07/30)
The invention relates to an influenza virus replication inhibitor and application thereof, and particularly relates to a compound serving as an influenza virus replication inhibitor, a preparation method thereof, a pharmaceutical composition containing the compound, and application of the compound and the pharmaceutical composition to influenza treatment.
INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF
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Paragraph 00284, (2018/07/31)
Provided herein is inhibitors of influenza virus replication and uses thereof. Specifically, provided herein a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF
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Paragraph 00298, (2018/09/21)
The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF
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Paragraph 00234, (2017/07/04)
The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits
B-Rao, Chandrika,Kulkarni-Almeida, Asha,Katkar, Kamlesh V.,Khanna, Smriti,Ghosh, Usha,Keche, Ashish,Shah, Pranay,Srivastava, Ankita,Korde, Vaidehi,Nemmani, Kumar V.S.,Deshmukh, Nitin J.,Dixit, Amol,Brahma, Manoja K.,Bahirat, Umakant,Doshi, Lalit,Sharma, Rajiv,Sivaramakrishnan
, p. 2930 - 2939 (2012/06/29)
In recent years, xanthine oxidase has emerged as an important target not only for gout but also for cardiovascular and metabolic disorders involving hyperuricemia. Contrary to popular belief, recent clinical trials with uricosurics have demonstrated that
A highly regioselective amination of 6-aryl-2,4-dichloropyrimidine
Peng, Zhi-Hui,Journet, Michel,Humphrey, Guy
, p. 395 - 398 (2007/10/03)
A highly regioselective amination of 6-aryl-2,4-dichloropyrimidine with aliphatic secondary amines and aromatic amines has been developed which strongly favors the formation of the C4-substituted product. The reactions with aliphatic amines are carried ou
NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM
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Page/Page column 287, (2008/06/13)
The present invention provides new heterocyclic compounds, particularly substituted pyrimidines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.
Coating compositions stabilized against damage by light, heat and oxygen
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Page column 44, (2008/06/13)
Coatings comprisingA) a binder based on an organic polymer andB) as stabilizer against damage by light, heat and oxygen, a 2-(2′-hydroxyphenyl)-1,3-pyrimidine of the formula I ?in which the radicals R1 to R6 are as defined in claim 1 have an outstanding resistance to the damaging effects of light, oxygen and heat. Compounds of the formula Ib defined in claim 18 are suitable in general for the stabilization of organic material.
Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
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Example Pr3, (2008/06/13)
This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae: wherein Z1, Z2, R1, R2, R3, R4, R5and R6are defined herein. These compounds are useful as anti-coagulants.
