17511-19-2Relevant academic research and scientific papers
Synthesis of 6-aryl-2,4-diamino-pyrimidines and triazines using palladium catalysed Suzuki cross-coupling reactions
Cooke,Augier de Cremiers,Rotello,Tarbit,Vanderstraeten
, p. 2787 - 2789 (2001)
The high yielding synthesis of 6-aryl-2,4-diaminopyrimidines and triazines via palladium catalysed Suzuki cross-coupling reactions of commercially available 6-chloro-2,4-diaminopyrimidine 1 or 6-chloro-2,4-diaminotriazine 8 and aryl boronic acids are desc
Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits
B-Rao, Chandrika,Kulkarni-Almeida, Asha,Katkar, Kamlesh V.,Khanna, Smriti,Ghosh, Usha,Keche, Ashish,Shah, Pranay,Srivastava, Ankita,Korde, Vaidehi,Nemmani, Kumar V.S.,Deshmukh, Nitin J.,Dixit, Amol,Brahma, Manoja K.,Bahirat, Umakant,Doshi, Lalit,Sharma, Rajiv,Sivaramakrishnan
, p. 2930 - 2939 (2012/06/29)
In recent years, xanthine oxidase has emerged as an important target not only for gout but also for cardiovascular and metabolic disorders involving hyperuricemia. Contrary to popular belief, recent clinical trials with uricosurics have demonstrated that
A new method for the synthesis of 2,4-diamino-6-arylpyrimidines
Nenajdenko,Golubinskii,Lenkova,Shastin,Balenkova
, p. 255 - 256 (2007/10/03)
A method for the synthesis of 2,4-diamino-6-arylpyrimidines from guanidine and α-chlorocinnamonitriles was developed. The starting nitriles can be easily prepared by catalytic olefination reaction.
