163394-61-4Relevant academic research and scientific papers
Highly diastereoselective addition of methyl 2-(N-benzylamino)-1-cyclohexenecarboxylate to chiral acrylates
Hervouet, Katia,Guingant, Andre
, p. 425 - 426 (1996)
Conjugate addition reaction of achiral methyl 2-(N-benzylamino)-1-cyclohexenecarboxylate 2 to chiral acrylates 4a,4b,4c led, after treatment of the primary adducts with sodium methoxyde, to α,α-disubstituted β-keto ester 1 with high enantiomeric excesses.
Highly diastereoselective addition of cyclic β-enamino esters to N-acryloyl-(S)-proline derivatives
Hervouet, Katia,Guingant, Andre
, p. 421 - 424 (1996)
Considerable asymmetric induction can be obtained by reacting cyclic β-enamino esters with chiral acrylamides derived from (S)-proline in the presence of Lewis acids.
Methyl Methacrylate as Acceptor in the Asymmetric Michael Reaction Using Chiral β-Enaminoesters: Simultaneous, Complete Stereocontrol of a Quaternary Carbon Center and a Tertiary One in the β-Position
Cave, Christian,Daley, Valerie,d'Angelo, Jean,Guingant, Andre
, p. 79 - 82 (2007/10/02)
Addition of enaminoester (R)-7 to methyl methacrylate 8 led to adduct (2S,1'R)-9 with a complete stereoselectivity.
