163434-34-2Relevant academic research and scientific papers
A nickel(ii)-catalyzed asymmetric intramolecular Alder-ene reaction of 1,7-dienes
Liu, Wen,Zhou, Pengfei,Lang, Jiawen,Dong, Shunxi,Liu, Xiaohua,Feng, Xiaoming
, p. 4479 - 4482 (2019/04/26)
A highly diastereo- and enantioselective intramolecular Alder-ene reaction with an alkene as the enophile has been developed by using a chiral N,N′-dioxide/nickel(ii) complex as the catalyst. This protocol provides a facile route towards the synthesis of diverse 3,4-disubstituted chroman, tetrahydroquinoline, piperidine and thiochroman derivatives in high yields with good to excellent diastereo- and enantioselectivities.
INTRAMOLECULAR ENE REACTIONS VS COMPETITIVE PERICYCLIC PROCESSES: THE EFFECT OF SOLVENTS AND SALTS ON THE REACTION OF 5-BROMO-2-(3-METHYL-2-BUTENYLOXY)BENZYLIDENEMALONIC ACID DIMETHYL ESTER
Desimoni, Giovanni,Faita, Giuseppe,Righetti, Pier Paolo,Vietti, Francesca
, p. 817 - 830 (2007/10/02)
The reactivity of 5-bromo-2-(3-methyl-2-butenyloxy)benzylidene malonic acid dimethyl ester (3) was studied in several reaction media.In aprotic solvents intramolecular ene reaction (IER) occurred to give cis and trans chroman derivatives (4) and (5), and
