1635-28-5 Usage
Uses
Used in Pharmaceutical Industry:
2-(DIMETHYLAMINO)-4(1H)-PYRIMIDINONE is used as a building block for the synthesis of pharmaceuticals, specifically in the production of antiviral and antitumor drugs. Its unique chemical structure allows for the development of new and effective medications to combat various diseases.
Used in Agrochemical Industry:
2-(DIMETHYLAMINO)-4(1H)-PYRIMIDINONE is also used as a building block in the synthesis of agrochemicals. Its properties make it suitable for the development of new pesticides and other agricultural products to improve crop yield and protect plants from diseases and pests.
Used in Parkinson's Disease Treatment Research:
2-(DIMETHYLAMINO)-4(1H)-PYRIMIDINONE has been investigated for its potential use in the treatment of Parkinson's disease. Its chemical properties may offer new therapeutic approaches for managing the symptoms and progression of this neurodegenerative disorder. Further research is needed to fully understand its potential applications in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 1635-28-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,3 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1635-28:
(6*1)+(5*6)+(4*3)+(3*5)+(2*2)+(1*8)=75
75 % 10 = 5
So 1635-28-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H9N3O/c1-9(2)6-7-4-3-5(10)8-6/h3-4H,1-2H3,(H,7,8,10)
1635-28-5Relevant academic research and scientific papers
Cyclopalladation in the Periphery of a NHC Ligand as the Crucial Step in the Synthesis of Highly Active Suzuki–Miyaura Cross-Coupling Catalysts
Fizia, Agnes,Gaffga, Maximilian,Lang, Johannes,Sun, Yu,Niedner-Schatteburg, Gereon,Thiel, Werner R.
, p. 14563 - 14575 (2017/10/07)
Starting from 2,4-dichloropyrimidine, 4-(2-dialkylamino)pyrimidinyl functionalized mesitylimidazolium chlorides are accessible in a five-step reaction sequence. Two routes leading to palladium NHC complexes derived from these ligands have been worked out: By transmetalation with the corresponding NHC-AgCl complexes, C,N-coordinated palladium(II) complexes can be obtained. Treatment of palladium dichloride with the imidazolium salts in pyridine and in the presence of K2CO3 gives cyclometalated and thus C,C-coordinated compounds. The reactivities of all these compounds were investigated in detail as well as their performance in the catalytic Suzuki–Miyaura cross-coupling reaction. It turned out that the C,C-coordinated derivatives exhibit high catalytic activities in the coupling of arylboronic acids with aryl chlorides, which is consistent with the generally accepted mechanistic ideas on substrate activation.
