163518-08-9Relevant academic research and scientific papers
Use of Light-Degradable Aliphatic Polycarbonate Nanoparticles As Drug Carrier for Photosensitizer
Sun, Jingjiang,Birnbaum, Wolfgang,Anderski, Juliane,Picker, Marie-Theres,Mulac, Dennis,Langer, Klaus,Kuckling, Dirk
, p. 4677 - 4690 (2018)
Aliphatic poly(carbonate)s (APCs) with rapid and controlled degradation upon specific stimulation have great advantages for a variety of biomedical and pharmaceutical applications. In the present work, we reported a new poly(trimethylene carbonate) (PTMC)
POLYMER-PARTICLE LIGHT-CLEAVABLE CARRIER SYSTEMS FOR PHOTODYNAMIC THERAPY
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Page/Page column 33-34, (2020/05/13)
The present invention generally relates to the formation, chemistry and application of biologically active compositions. More particularly, the present invention relates to certain dyes, specifically porphyrin and chlorin derivatives, in combination with
External-Radiation-Induced Local Hydroxylation Enables Remote Release of Functional Molecules in Tumors
Duan, Dongban,Fu, Qunfeng,Li, Hongyu,Liu, Zhibo,Ma, Huimin,Shen, Siyong,Wang, Changlun
supporting information, p. 21546 - 21552 (2020/09/07)
Radiation-induced cleavage for controlled release in vivo is yet to be established. We demonstrate the use of 3,5-dihydroxybenzyl carbamate (DHBC) as a masking group that is selectively and efficiently removed by external radiation in vitro and in vivo. D
Synthesis of photocaged diamines and their application in photoinduced self-assembly
Barra, Tomas,Arrue, Lily,Urzúa, Esteban,Ratjen, Lars
, (2019/02/06)
The photochemical cleavage of covalent bonds is an important strategy in protection group chemistry, as well as for the triggering of chemical events posterior to the application of the physicochemical stimulus. Photocages allow the arresting and traceles
UV and near-IR triggered release from polymeric nanoparticles
Fomina, Nadezda,McFearin, Cathryn,Sermsakdi, Marleen,Edigin, Osayimwense,Almutairi, Adah
supporting information; experimental part, p. 9540 - 9542 (2010/08/20)
A new light-sensitive polymer containing multiple light-sensitive triggering groups along the backbone and incorporating a quinone-methide self-immolative moiety was developed and formulated into nanoparticles encapsulating a model pharmaceutical Nile Red. Triggered burst release of the payload upon irradiation and subsequent degradation of the nanoparticles were observed. This system is designed to be versatile where the triggering group can be sensitive to a number of wavelengths.
Photolabile protecting group bonded to aminopropyl silica-gel beads
Matsumoto, Jin,Senda, Yoshiya,Masuda, Hiroki,Fuchikawa, Tomokazu,Shiragami, Tsutomu,Yasuda, Masahide
experimental part, p. 997 - 999 (2011/03/21)
4, 5-Dimethoxy-2-nitrobenzyloxycarbonyl group acting as a photolabile protecting group was bonded on 3-amino- propyl silica gels through a covalent bond ina 46% yield. The deprotection was performed under UV-irradiation. The resulting amino group was anal
Base Multiplying Agents and Base-Reactive Curable Compositions
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Page/Page column 10-11, (2008/12/08)
To provide such a base multiplying agent capable of being used for crosslinking reaction, for example of a epoxy compound and the like, that generates another base by action of a base, and can efficiently perform base multiplying reaction, and a base-reactive curable composition using the base multiplying agent. The base generating agent of the invention is represented by the following formula (1): (In the formula (1), X represents a hydrogen atom, a substituted alkyl group or an unsubstituted alkyl group; Y represents a substituted or unsubstituted alkylene chain; and n represents an integer of from 1 to 4.)
