16360-98-8

Basic information

• Product Name: (perfluoropyridin-4-yl)(phenyl)methanol
• CAS NO: 16360-98-8
• Molecular Weight: 257.187
• Mol File: 16360-98-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (perfluoropyridin-4-yl)(phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (perfluoropyridin-4-yl)(phenyl)methanol(16360-98-8)
• EPA Substance Registry System: (perfluoropyridin-4-yl)(phenyl)methanol(16360-98-8)

Safety Data

• Hazardous Substances Data: 16360-98-8(Hazardous Substances Data)

Upstream product

• 700-16-3 Pentafluoropyridine 
• 52026-98-9 4-chloro-2,3,5,6-tetrafluoropyridine 
• 100-52-7 benzaldehyde 
• 18303-86-1 (2,3,5,6-tetrafluoro pyridyl) magnesiumiodide 

Relevant articles and documents

SNAr catalysis enhanced by an aromatic donor-acceptor interaction; Facile access to chlorinated polyfluoroarenes

Selective catalytic SNAr reaction of polyfluoroaryl C-F bonds with chloride is shown. Stoichiometric TMSCl makes the reaction exergonic and allows catalysis, which involves ground state elevation of chloride, aromatic donor-acceptor interactions, and stabilization of the Meisenheimer complex. Traditional cross-coupling of the products is now possible and demonstrates the utility.