52026-98-9 Usage
General Description
4-Chloro-2,3,5,6-tetrafluoropyridine is a chemical compound with the molecular formula C5HClF4N. It is a highly stable and non-reactive compound, commonly used as an intermediate in the production of pharmaceuticals and agrochemicals. 4-Chloro-2,3,5,6-tetrafluoropyridine is a clear, colorless liquid with a slightly sweet odor. It is soluble in organic solvents and has a low volatility, making it relatively easy to handle in industrial processes. The presence of a chlorine atom and four fluorine atoms in the molecule makes 4-Chloro-2,3,5,6-tetrafluoropyridine highly electronegative, making it useful in a variety of chemical reactions. Therefore, it is used as a building block in the synthesis of various complex organic compounds for use in the pharmaceutical and agricultural industries.
Check Digit Verification of cas no
The CAS Registry Mumber 52026-98-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,0,2 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 52026-98:
(7*5)+(6*2)+(5*0)+(4*2)+(3*6)+(2*9)+(1*8)=99
99 % 10 = 9
So 52026-98-9 is a valid CAS Registry Number.
InChI:InChI=1/C5ClF4N/c6-1-2(7)4(9)11-5(10)3(1)8
52026-98-9Relevant articles and documents
Organocatalyzed Fluoride Metathesis
Mulryan, Daniel,White, Andrew J. P.,Crimmin, Mark R.
supporting information, p. 9351 - 9355 (2020/11/30)
A new organocatalyzed fluoride metathesis reaction between fluoroarenes and carbonyl derivatives is reported. The reaction exchanges fluoride (F-) and alternate nucleophiles (OAc-, OCO2R-, SR-, Cl-, CN-, NCS-). The approach provides a conceptually novel route to manipulate the fluorine content of organic molecules. When the fluorination and defluorination steps are combined into a single catalytic cycle, a byproduct free and 100% atom-efficient reaction can be achieved.
POLYHALOAROMATIC EQUILIBRATIONS
Weigert, F. J.
, p. 33 - 42 (2007/10/02)
Chromium oxide is a good catalyst for scrambling halogens among polyhaloaromatic compounds.Chloropentafluorobenzene and bromopentafluorobenzene disproportionate to hexafluorobenzene and the respective tetrafluorodihalobenzenes.Pentachloro- and pentafluoropyridines produce pyridines with intermediate numbers of both types of halogens.Cyano, trifluoromethyl and a single hydrogen can be present on the aromatic rings without interfering with the chemistry.