163704-72-1

Basic information

• Product Name: 2,6-DIISOPROPYL-4-NITROANILINE
• Synonyms: 2,6-DIISOPROPYL-4-NITROANILINE
• CAS NO: 163704-72-1
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.28
• Product Categories: pharmacetical
• Mol File: 163704-72-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 125-126 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
• Boiling Point: 333 °C at 760 mmHg
• Flash Point: 155.2 °C
• Appearance: /
• Density: 1.091 g/cm³
• Vapor Pressure: 0.000141mmHg at 25°C
• Refractive Index: 1.555
• PKA: 0.70±0.20(Predicted)
• CAS DataBase Reference: 2,6-DIISOPROPYL-4-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIISOPROPYL-4-NITROANILINE(163704-72-1)
• EPA Substance Registry System: 2,6-DIISOPROPYL-4-NITROANILINE(163704-72-1)

Safety Data

• Hazardous Substances Data: 163704-72-1(Hazardous Substances Data)

Usage

General Description

2,6-DIISOPROPYL-4-NITROANILINE is a chemical compound with the molecular formula C13H19N3O2. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. The chemical is a yellow crystalline solid that is insoluble in water but soluble in organic solvents. It is also known as DINAN, and it is primarily used as a synthetic intermediate in the production of dyes, pigments, and other organic compounds. The compound is considered to be of low toxicity, but it should be handled with care and in accordance with proper safety guidelines when used in industrial settings.

InChI:InChI=1/C12H18N2O2/c1-7(2)10-5-9(14(15)16)6-11(8(3)4)12(10)13/h5-8H,13H2,1-4H3

Upstream product

• 163704-71-0 N-(2,6-diisopropylphenyl)tosylamide 
• 24544-04-5 2,6-diisopropylbenzenamine 
• 474328-43-3 N-(2,6-diisopropyl-4-nitrophenyl)-4-methylbenzenesulfonamide 

Downstream Products

• 849472-27-1 N,N’-bis-(2,6-diisopropyl,4-nitrophenyl)-2,3-dimethyl-1,4-diaza-1,3-butadiene 
• 1422237-06-6 C₄₉H₆₆N₄O₃ 
• 1341123-94-1 2-(1-(2,6-diisopropyl-4-nitrophenylimino)ethylidene)-8-methylquinoline 
• 1197825-17-4 2,6-diisopropyl-4-nitroanil-2,6-diactylpyridine 
• 476371-02-5 tert-butyl [4-({[(4-{3-[3-(benzyloxy)propoxy]phenyl}-1-butyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)amino]carbonyl}amino)-3,5-diisopropylphenyl]carbamate 
• 437763-93-4 tert-butyl (4-{[({1-butyl-4-[3-(3-hydroxypropoxy)phenyl]-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl}-amino)carbonyl]amino}-3,5-diisopropylphenyl)carbamate 
• 437763-60-5 tert-butyl (4-amino-3,5-diisopropylphenyl)carbamate 
• 873194-95-7 1-{1-butyl-2-oxo-4-[3-(3-piperidin-1-yl-propoxy)-phenyl]-1,2-dihydro-[1,8]naphthyridin-3-yl}-3-[2,6-diisopropyl-4-(trityl-amino)-phenyl]-urea 

Relevant articles and documents

Synthesis method of diafenthiuron impurity C

The invention provides a preparation method of a diafenthiuron impurity C. According to the preparation method of the diafenthiuron impurity C, 2, 6-isopropylaniline, 4-toluenesulfonyl chloride, phenol, N, N-diisopropylethylamine and the like are used as

Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)- on-3-yl ureas: Potent acyl-CoA:cholesterol acyltransferase inhibitor with improved aqueous solubility

4-Aryl-1,8-naphthyridin-2(1H)-on-3-yl urea derivatives with hydrophilic groups were synthesized in order to improve aqueous solubility and pharmacokinetic property. SMP-797 possessing (4-aminophenyl)ureido and 3-(hydroxypropoxyphenyl) moieties showed pote

Substituent effects on edge-to-face aromatic interactions

Chemical double mutant cycles have been used to measure the magnitude of edge-to-face aromatic interactions in hydrogen-bonded zipper complexes as a function of substituents on both aromatic rings. The interaction energies vary depending on the combinatio