476371-02-5

Basic information

• Product Name: Carbamic acid, [4-[[[[1-butyl-1,2-dihydro-2-oxo-4-[3-[3-(phenylmethoxy)propoxy]phenyl]- 1,8-naphthyridin-3-yl]amino]carbonyl]amino]-3,5-bis(1-methylethyl)phen yl]-, 1,1-dimethylethyl ester
• CAS NO: 476371-02-5
• Molecular Formula: C46H57N5O6
• Molecular Weight: 775.988
• Mol File: 476371-02-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [4-[[[[1-butyl-1,2-dihydro-2-oxo-4-[3-[3-(phenylmethoxy)propoxy]phenyl]- 1,8-naphthyridin-3-yl]amino]carbonyl]amino]-3,5-bis(1-methylethyl)phen yl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [4-[[[[1-butyl-1,2-dihydro-2-oxo-4-[3-[3-(phenylmethoxy)propoxy]phenyl]- 1,8-naphthyridin-3-yl]amino]carbonyl]amino]-3,5-bis(1-methylethyl)phen yl]-, 1,1-dimethylethyl ester(476371-02-5)
• EPA Substance Registry System: Carbamic acid, [4-[[[[1-butyl-1,2-dihydro-2-oxo-4-[3-[3-(phenylmethoxy)propoxy]phenyl]- 1,8-naphthyridin-3-yl]amino]carbonyl]amino]-3,5-bis(1-methylethyl)phen yl]-, 1,1-dimethylethyl ester(476371-02-5)

Safety Data

• Hazardous Substances Data: 476371-02-5(Hazardous Substances Data)

Upstream product

• 591-20-8 3-Bromophenol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 54314-84-0 1-[(3-bromopropoxy)methyl]-benzene 
• 476370-97-5 1-butyl-2-oxo-1,2-dihydro-1,8-naphthyridin-4-yl acetate 
• 139482-07-8 1-butyl-4-hydroxy-3-nitro-1,8-naphthyridin-2(1H)-one 
• 139482-08-9 1-butyl-4-chloro-3-nitro-1,8-naphthyridin-2(1H)-one 
• 74611-53-3 2-(butylamino)nicotinic acid 
• 24544-04-5 2,6-diisopropylbenzenamine 
• 2942-59-8 2-chloronicotinic acid 
• 259225-38-2 3-amino-4-{3-[3-(benzyloxy)propoxy]phenyl}-1-butyl-1,8-naphthyridin-2(1H)-one 
• 476371-00-3 4-{3-[3-(benzyloxy)propoxy]phenyl}-1-butyl-3-nitro-1,8-naphthyridin-2(1H)-one 
• 476370-99-7 {3-[3-(benzyloxy)propoxy]phenyl}boronic acid 
• 455288-51-4 4-amino-2,6-diisopropylaniline 
• 437763-60-5 tert-butyl (4-amino-3,5-diisopropylphenyl)carbamate 

Downstream Products

• 437763-93-4 tert-butyl (4-{[({1-butyl-4-[3-(3-hydroxypropoxy)phenyl]-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl}-amino)carbonyl]amino}-3,5-diisopropylphenyl)carbamate 

Relevant articles and documents

Synthesis of SMP-797: A new potent ACAT inhibitor

A potent ACAT (acyl-CoA: cholesterol acyltransferase) inhibitor SMP-797 was effectively synthesized by the urea formation of 3-amino-4-aryl-1,8- naphthyridin-2(1H)-one and 4-amino-2,6-diisopropylamine. The synthesis of the former compound involved the Suzuki coupling reaction as a key step, and the latter was prepared by the 4-selective nitration of 2,6-diisopropylaniline using 2,3,5,6-tetrabromo-4-methyl-4-nitro-2,5-cyclohexadienone.