1638238-20-6

Basic information

• Product Name: 5-isopropyl-2,3-diphenyl-1H-indole
• Synonyms: 5-isopropyl-2,3-diphenyl-1H-indole
• CAS NO: 1638238-20-6
• Molecular Weight: 311.426
• Mol File: 1638238-20-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-isopropyl-2,3-diphenyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-isopropyl-2,3-diphenyl-1H-indole(1638238-20-6)
• EPA Substance Registry System: 5-isopropyl-2,3-diphenyl-1H-indole(1638238-20-6)

Safety Data

• Hazardous Substances Data: 1638238-20-6(Hazardous Substances Data)

Upstream product

• 1817-47-6 4-nitrocumene 
• 501-65-5 diphenyl acetylene 
• 451-40-1 phenyl benzyl ketone 
• 63693-65-2 4-isopropylphenylhydrazine 
• 99-88-7 4-Isopropylaniline 
• 118427-29-5 (4-isopropylphenyl)hydrazine hydrochloride 

Relevant articles and documents

Step and redox efficient nitroarene to indole synthesis

Step and redox efficiencies are a rising priority in synthetic method development, in order to make synthetic processes more sustainable and more affordable. Herein, a step and redox efficient nitroarene to indole synthesis is developed, in sharp contrast to the rich literature on the construction of indoles. Elemental zinc was found to be the best terminal reductant. This journal is

Regioselective synthesis of indoles via rhodium-catalyzed C-H activation directed by an in-situ generated redox-neutral group

A regioselective synthesis of indoles from arylhydrazine hydrochlorides with alkynes and diethyl ketone catalyzed by a rhodium complex is described. A possible mechanism involving an in-situ generated oxidizing directing group -N-Ni'CR1R2 assisted ortho-C-H activation and reductive elimination are proposed. The catalytic reaction is highly compatible with a wide range of functional arylhydrazines and alkynes. The reaction proceeds under mild reaction conditions and is atom-step economical.