1133-12-6

Usage

Uses

Used in Plastics and Polymer Industry:
N-Propyl-P-Toluenesulfonamide is used as a plasticizer for enhancing the flexibility and viscosity of polymers such as PVC, polyurethane, and acrylics. It contributes to the improved performance and properties of these materials by acting as a processing aid.
Used as a Flame Retardant:
In the flame retardant industry, N-Propyl-P-Toluenesulfonamide is utilized to improve the fire resistance of materials, leveraging its high thermal stability to prevent or slow down the spread of flames.
Used as a Lubricant Additive:
In the lubricant industry, N-Propyl-P-Toluenesulfonamide serves as an additive to enhance the performance of lubricants, providing better thermal stability and reducing wear and tear on machinery.
Used in Personal Care Products:
N-Propyl-P-Toluenesulfonamide is used in the formulation of some personal care products, where it contributes to the product's texture, stability, and performance.
Used in Pharmaceutical Formulation:
In the pharmaceutical industry, N-Propyl-P-Toluenesulfonamide is employed in the development of certain medications, potentially enhancing their efficacy and stability.

InChI:InChI=1/C10H15NO2S/c1-3-8-11-14(12,13)10-6-4-9(2)5-7-10/h4-7,11H,3,8H2,1-2H3

Upstream product

• 107-10-8 propylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 106-94-5 propyl bromide 
• 18522-92-4 sodium p-toluenesulfonamide 
• 123-38-6 propionaldehyde 
• 4104-47-6 N-sulfinyl-p-toluenesulfonamide 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 111-43-3 Dipropyl ether 
• 70-55-3 toluene-4-sulfonamide 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 
• 13380-02-4 N-(3-iodo-propyl)-4-methyl-benzenesulfonamide 
• 104-15-4 toluene-4-sulfonic acid 
• 163926-77-0 4-methyl-N-[propylidene]benzene-1-sulfonamide 

Downstream Products

• 7302-00-3 (E)-1,3-diphenyl-1-butene 
• 738587-84-3 N-(acridine-9-carbonyl)-4-methyl-N-propyl-benzenesulfonamide 
• 853063-10-2 4-methyl-N-(prop-2-ynyl)-N-propylbenzenesulfonamide 
• 1357913-18-8 (E)-N-(3-cyclohexyl-3-oxoprop-1-enyl)-4-methyl-N-propylbenzenesulfonamide 
• 1357913-08-6 (E)-4-methyl-N-(4-methyl-3-oxopent-1-enyl)-N-propylbenzenesulfonamide 
• 1357913-17-7 (E)-N-(3-cyclopentyl-3-oxoprop-1-enyl)-4-methyl-N-propylbenzenesulfonamide 
• 1391911-31-1 C₁₅H₂₅NO₃S 
• 1392414-65-1 (Z)-N-(1-bromo-1-octen-2-yl)-N-propyl-p-toluenesulfonamide 
• 1375415-68-1 N-propyl-N-(phenylethynyl)-4-methylbenzenesulfonamide 
• 113845-16-2 N-fluoro-4-methyl-N-propylbenzenesulfonamide 
• 109949-95-3 N-(1,1-dimethoxypropan-2-yl)-4-methylbenzenesulfonamide 
• 1263053-71-9 N-(cyclopropylethynyl)-4-methyl-N-propylbenzenesulfonamide 

Relevant academic research and scientific papers

Design, synthesis, characterization and computational docking studies of novel sulfonamide derivatives

This study reports three novel sulfonamide derivatives 4-Chloro-N-[(4-methylphenyl) sulphonyl]-N-propyl ben-zamide (1A), N-(2-hydroxyphenyl)-4-methyl benzene sulfonamide (1B) and 4-methyl-N-(2-nitrophenyl) benzene sulfonamide (1C). The compounds were synt

Synthesis of N-substituted sulfonamides containing perhalopyridine moiety as bio-active candidates

A series of new halogenated aryl sulfonamides, as bio-active candidates, was synthesized from the reaction of the corresponding aryl sulfonamides with pentafluoro- and pentachloropyridines. Surprisingly, unlike aryl sulfonamides, the reaction of sulfamides with pentafluoro- and pentachloropyridines gave unexpected bis-perfluoro(chloro)pyridin-4-ylamines.

A study of [Co2(alkyne)(binap)(CO)4] complexes (BINAP = (1,1′-Binaphthalene)-2,2-diylbis(diphenylphosphine))

Understanding the interaction of chiral ligands, alkynes, and alkenes with cobaltcarbonyl sources is critical to learning more about the mechanism of the catalytic, asymmetric Pauson-Khand reaction. We have successfully characterized complexes of the type

Ligand-Controlled Regiodivergence for Catalytic Stereoselective Semireduction of Allenamides

Ligand-controlled regiodivergence has been developed for catalytic semireduction of allenamides with excellent chemo- and stereocontrol. This system also provides an example of catalytic regiodivergent semireduction of allenes for the first time. The divergence of the semireduction is enabled by ligand switch with the same palladium pre-catalyst under operationally simple and mild conditions. Monodentate ligand XPhos exclusively promotes selective 1,2-semireduction to afford allylic amides, while bidentate ligand BINAP completely switched the regioselectivity to 2,3-semireduction, producing (E)-enamide derivatives.

Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

Herein we report a Ni-catalyzed reductive transamidation of conveniently available N-acyl benzotriazoles with alkyl, alkenyl, and aryl nitro compounds, which afforded various amides with good yields and a broad substrate scope. The same catalytic reaction conditions were also applicable for N-sulfonyl benzotriazoles, which could undergo smooth reductive coupling with nitroarenes and nitroalkanes to afford the corresponding sulfonamides.

Nickel/Photoredox Dual Catalytic Cross-Coupling of Alkyl and Amidyl Radicals to Construct C(sp3)-N Bonds

The construction of C(sp3)-N bonds via direct radical-radical cross-coupling under benign conditions is a desirable but challenging approach. Herein, the cross-coupling of alkyl and amidyl radicals to build aliphatic C-N bonds in a concise, mild, and oxid

Facile synthesis of sulfonyl chlorides/bromides from sulfonyl hydrazides

A simple and rapid method for efficient synthesis of sulfonyl chlorides/bromides from sulfonyl hydrazide with NXS (X = Cl or Br) and late-stage conversion to several other functional groups was described. A variety of nucleophiles could be engaged in this transformation, thus permitting the synthesis of complex sulfonamides and sulfonates. In most cases, these reactions are highly selective, simple, and clean, affording products at excellent yields.

Catalyst-Free Visible-Light-Mediated Iodoamination of Olefins and Synthetic Applications

Herein we report a catalyst- and metal-free visible-light-mediated protocol enabling the iodoamination of miscellaneous olefins. This protocol is characterized by high yields under environmentally benign reaction conditions utilizing commercially available substrates and a green and biodegradable solvent. Furthermore, the protocol allows for late-stage functionalization of bioactive molecules and can be scaled to gram quantities of product, which offers manifold possibilities for further transformations, including morpholine, piperidine, pyrrolidine, and aziridine synthesis.

Cobalt-catalyzed alkene hydrogenation by reductive turnover

Earth abundant metal catalysts hold advantages in cost, environmental burden and chemoselectivity over precious metal catalysts. Differences in reactivity for a given metal center result from ligand field strength, which can promote reaction through either open- or closed-shell carbon intermediates. Herein we report a simple protocol for cobalt-catalyzed alkene reduction. Instead of using an oxidative turnover mechanism that requires stoichiometric hydride, we find a reductive turnover mechanism that requires stoichiometric proton. The reaction mechanism appears to involve coordination and hydrocobaltation of terminal alkenes.

Reductions of Imines Using Zirconocene Chloride Hydride

Herein, we describe the fast, chemoselective, and clean reduction of imines with zirconocene chloride hydride. The reaction works well on aromatic and enolizable aliphatic aldimines, as well as ketimines. A range of N-protecting groups and various functio