1639450-50-2Relevant academic research and scientific papers
Effect of substituents on the regioselectivity of the reaction of α-tosyloxyketones with thioureas in acidic medium: Access to 2-aminothiazoles and 2-imino-2,3-dihydrothiazoles
Aggarwal, Ranjana,Kumar, Rajiv,Sanz, Dionisia,Claramunt, Rosa M.
, p. 598 - 603 (2014/06/10)
Regioselective condensation of α-tosyloxyacetophenones 1 and N-substituted thioureas 2 in acidic medium to give regioisomers 2-aminothiazoles I and 2-imino-2,3-dihydrothiazoles II is largely influenced by the substituents present on 1 and 2. A mechanism,
