163956-16-9

Usage

Uses

Used in Pharmaceutical Industry:
Kaempferol-3-O-(6''-O-cis-coumaryl)glucoside is used as a therapeutic agent for its antioxidant, anti-inflammatory, and anti-cancer properties. Its ability to modulate various biological pathways and exhibit inhibitory effects on tumor growth and progression makes it a promising candidate for the development of novel pharmaceuticals targeting various health conditions.
Used in Nutraceutical Industry:
Astragalin is used as a dietary supplement for its potential health benefits, including supporting cardiovascular health and managing diabetes by improving glucose metabolism. Its presence in various plant-based foods and its potential neuroprotective effects also contribute to its use in the development of nutraceutical products aimed at promoting overall health and well-being.
Used in Cosmetic Industry:
Kaempferol-3-O-(6''-O-cis-coumaryl)glucoside is used as an active ingredient in cosmetic products for its antioxidant and anti-inflammatory properties. Its potential to protect the skin from oxidative stress and reduce inflammation can contribute to the development of skincare products that promote healthy and youthful-looking skin.
Used in Functional Food Industry:
Astragalin is used as a functional ingredient in food products to enhance their health-promoting properties. Its presence in various plant-based foods and its potential to support cardiovascular health, manage diabetes, and offer neuroprotective effects make it a valuable addition to functional foods aimed at improving overall health and well-being.

Upstream product

• 20316-62-5 Tiliroside 
• 74712-68-8 kaempferol 3-O-(3'',6''-di-O-E-p-coumaroyl)-β-D-glucopyranoside 
• 256442-36-1 6''-O-p-coumaroylastragalin heptaacetate 
• 22153-44-2 trans-tiliroside 

Downstream Products

• 50-99-7 D-glucose 
• 520-18-3 kaempferol 

Relevant academic research and scientific papers

A highly efficient transformation of cis- to trans-cinnamic acid derivatives by iodine

Cinnamic acid derivatives (CAs), which have proven to be versatile components, are present in abundance in biologically active natural products, and are widely used as intermediates in the manufacture of pharmaceuticals, and chemicals. The presence of cis- and trans-CAs created difficulties for natural product and organic synthetic studies. A highly efficient method that utilized iodine to entirely convert cis- CAs into their trans-forms was developed to solve this problem. The mechanism of study revealed this conversion occurred via an anti-diiodo intermediate.

Acylated flavonol diglucosides from Lotus polyphyllos

Three acylated flavonol diglucosides, kaempferol 3-O-β -(6″-O-E-p-coumaroylglucoside)-7-O-β-glucoside; quercetin 3- O-β-(6″-O-E-p-coumaroylglucoside)-7-O-β-glucoside; isorhamnetin 3-O-β-(6″-O-E-p-coumaroylglucoside)-7-O-β-glucoside were isolated from the

Structure Elucidation and Synthesis of Flavonol Acylglycosides. III. The Synthesis of Tiliroside

Naturally occurring kaempferol 3-O-β-D-(6''-O-coumaroyl)glucopyranoside (tiliroside) has been synthesized thereby confirming its structure.This is the first acylated flavonoid glycoside to be synthesized.

O-ACYLATED FLAVONOID GLYCOSIDES FROM THE NEEDLES OF Picea obovata II. 3''- and 6''-ISOMERS OF p-COUMAROYLASTRAGALIN

Two monoacylated glycosides have been isolated from the needles of Picea obovata - the previously unknown 3''-p-coumaroylastragalin (I) and 6''-p-coumaroylastragalin (II).It has been established that under the conditions of mild saponification and acid hydrolysis isomerization of (I) into (II) and the splitting out of the acid residue takes place.The position of the acyl substituent has been shown by PMR spectroscopy using the INDOR method.The physicochemical characteristics of the acylated glycosides and of their heptaacetates are given.