164021-52-7

Basic information

• Product Name: Toluene-4-sulfonic acid (Z)-2,3,3-trifluoro-1-methyl-propenyl ester
• CAS NO: 164021-52-7
• Molecular Weight: 280.268
• Mol File: 164021-52-7.mol

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid (Z)-2,3,3-trifluoro-1-methyl-propenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid (Z)-2,3,3-trifluoro-1-methyl-propenyl ester(164021-52-7)
• EPA Substance Registry System: Toluene-4-sulfonic acid (Z)-2,3,3-trifluoro-1-methyl-propenyl ester(164021-52-7)

Safety Data

• Hazardous Substances Data: 164021-52-7(Hazardous Substances Data)

Upstream product

• 786-31-2 p-toluenesulfonic acid-2,2,3,3-tetrafluoropropyl ester 
• 333-27-7 methyl trifluoromethanesulfonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 74-88-4 methyl iodide 

Relevant articles and documents

Facile generation of polyfluoro-1-(tosyloxy)prop-1-enyllithiums and their reaction with electrophiles. A new, efficient and convenient access to (Z)-1,1-di- and 1,1,1-tri-fluoro-3-(tosyloxy)alk-3-en-2-ones

Polyfluoro-1-(tosyloxy)prop-1-enyllithiums, generated by the reaction of polyfluoropropyl toluene-p-sulfonates or polyfluoroprop-1-enyl toluene-p-sulfonates with n-butyllithium, readily react with a variety of electrophiles, such as aldehydes, ketones, me

Reactions of 1-Substituted-polyfluoro-1-propenyl p-Toluenesulfonates with Bifunctional Nitrogen Nucleophiles. A New Expedient Access to Monofluorinated Nitrogen Heterocycles

1-Substituted-2,3,3-trifluoro-1-propenyl p-toluenesulfonates, readily available by the alkylation or arylation of 2,3,3-trifluoro-1-tosyloxy-1-propenyllithium or -zinc reagent, reacted smoothly with amidine or hydrazine derivatives at 70 deg C for 1h to give the corresponding 5-fluoropyrimidine or 4-fluoropyrazole compounds, respectively, in moderate to excellent yields.