164026-63-5Relevant academic research and scientific papers
Synthesis and biological evaluation of some tacrine analogs: Study of the effect of the chloro substituent on the acetylcholinesterase inhibitory activity
Ragab, Hanan M.,Ashour, Hayam M. A.,Galal, Amal,Ghoneim, Asser I.,Haidar, Hassan R.
, p. 539 - 552 (2016)
New tetrahydroquinoline derivatives were synthesized, characterized, and evaluated for their in vitro and in vivo acetylcholinesterase inhibitory activity as well as hepatotoxicity using tacrine as a reference standard. The obtained results revealed that
An efficient synthesis of pyrazolo[3,4- b]quinolin-3-amine and benzo[b][1,8]naphthyridine derivatives
Elkholy, Yehya M.
, p. 361 - 372 (2007/10/03)
2-Oxo-4-phenyl-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile (10) reacted with hydrazine hydrate, phenylisothiocyanate or benzoyl chloride to give derivatives 12, 13 and 15, respectively. The latter two products were treated with hydrazine hydrate to affo
Synthesis of some New Pyranes and Quinolines
Assy, M. G.,Hassanien, M. M.,Zaki, S. A.
, p. 371 - 375 (2007/10/02)
The reaction of cyclohexanone with cinnamonitriles under different conditions was studied. The possible annulation of resultant enaminonitrile using various reagents was also described. Key words: pyranes, quinolines, pyranopyrimidine, quinolinopyrimidine, pyranopyrazole, pyranopyridine
