164034-00-8

Basic information

• Product Name: (5R,6R)-7-Oxo-6-(2-oxo-4-phenyl-butyl)-3-phenoxymethyl-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester
• CAS NO: 164034-00-8
• Molecular Weight: 463.554
• Mol File: 164034-00-8.mol

Chemical Properties

• CAS DataBase Reference: (5R,6R)-7-Oxo-6-(2-oxo-4-phenyl-butyl)-3-phenoxymethyl-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (5R,6R)-7-Oxo-6-(2-oxo-4-phenyl-butyl)-3-phenoxymethyl-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester(164034-00-8)
• EPA Substance Registry System: (5R,6R)-7-Oxo-6-(2-oxo-4-phenyl-butyl)-3-phenoxymethyl-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester(164034-00-8)

Safety Data

• Hazardous Substances Data: 164034-00-8(Hazardous Substances Data)

Upstream product

• 16640-69-0 4-phenyl-1-(triphenylphosphoranylidene)butan-2-one 
• 164033-43-6 (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-oxo-4-phenyl-butyl)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester 
• 164033-61-8 3-Methyl-2-[(3R,4R)-2-oxo-3-(2-oxo-4-phenyl-butyl)-4-(2-phenoxy-acetylsulfanyl)-azetidin-1-yl]-but-2-enoic acid 2,2-dimethyl-propionyloxymethyl ester 
• 164033-73-2 2,2-Dimethyl-propionic acid 2-oxo-2-[(3R,4R)-2-oxo-3-(2-oxo-4-phenyl-butyl)-4-(2-phenoxy-acetylsulfanyl)-azetidin-1-yl]-acetoxymethyl ester 
• 164033-92-5 Phenoxy-thioacetic acid S-[(2R,3R)-4-oxo-3-(2-oxo-4-phenyl-butyl)-azetidin-2-yl] ester 
• 701-99-5 Phenoxyacetyl chloride 
• 74503-07-4 allyl oxalyl chloride 
• 164033-96-9 Oxo-[(3R,4R)-2-oxo-3-(2-oxo-4-phenyl-butyl)-4-(2-phenoxy-acetylsulfanyl)-azetidin-1-yl]-acetic acid allyl ester 

Relevant articles and documents

Synthesis of novel 6-α and 6-β-alkylcarbonylmethyl substituted penems

6-α and 6-β Alkylcarbonylmethyl penems were synthesized from 6-α-bromo and 6-oxo penicillanates respectively and their in vitro antibacterial activity was studied. The compounds were generally active against Gram-positive but not against Gram-negative strains, the compounds of the 6-β series being more active. Relatively to imipenem, taken as reference compound, the penems resulted more stable towards chemical hydrolysis in Tris-HCl buffered medium (pH 7.4) but more sensitive towards dehydropeptidase-I (DHP-I).