1642300-78-4 Usage
General Description
The chemical compound (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-(pyrimidin-5-yl)acrylamide is a type of acrylamide derivative. It contains a 1,2,4-triazole ring, a pyrimidine ring and two trifluoromethyl groups. (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-(pyrimidin-5-yl)acrylamide is commonly used as a pharmaceutical intermediate and may have potential applications in medicinal chemistry and drug discovery. It may also have biological activities and could be used as a building block to create new compounds with specific properties. The structure of this chemical makes it of interest for further research and development in various scientific fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1642300-78-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,4,2,3,0 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1642300-78:
(9*1)+(8*6)+(7*4)+(6*2)+(5*3)+(4*0)+(3*0)+(2*7)+(1*8)=134
134 % 10 = 4
So 1642300-78-4 is a valid CAS Registry Number.
1642300-78-4Relevant articles and documents
Azole derivative or pharmaceutically acceptable salt thereof as well as preparation method and application of azole derivative or pharmaceutically acceptable salt thereof
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, (2021/03/24)
The invention discloses an azole derivative or a pharmaceutically acceptable salt thereof and a preparation method of the azole derivative or pharmaceutically acceptable salt thereof. The structure ofthe azole derivative is as shown in the specification, and compared with the prior art, the invention provides an azole compound with a novel structure and a CRM1 protein inhibition function, and theazole compound is used as a CRM1 protein inhibitor and can block tumor cell proliferation and inhibit tumor cell apoptosis, and induce tumor cell apoptosis, and therefore, the compound can be used for treating and preventing various diseases of human and animals, such as malignant tumors, and the effect is remarkable and better.
