1642300-91-1 Usage
Description
(E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-bromoacrylic acid is a chemical compound belonging to the 1H-1,2,4-triazole class, characterized by its unique molecular structure featuring a 1,2,4-triazole ring, a bromoacrylic acid group, and trifluoromethyl substituents. (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-bromoacrylic acid is known for its potential applications in medicinal chemistry and chemical biology research due to its diverse biological activities and unique physicochemical properties.
Uses
Used in Medicinal Chemistry:
(E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-bromoacrylic acid is used as a building block for the development of new pharmaceuticals, leveraging its potential pharmacological activity and diverse biological properties. The presence of the 1,2,4-triazole ring and the bromoacrylic acid group allows for the creation of various drug candidates with possible therapeutic applications.
Used in Chemical Biology Research:
In the field of chemical biology, (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-bromoacrylic acid serves as a valuable compound for studying the interactions between small molecules and biological targets. Its unique structure and functional groups enable it to be used in the design and synthesis of bioactive molecules for probing biological systems and understanding complex cellular processes.
Used in Organic Synthesis:
The presence of the bromo group in (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-bromoacrylic acid makes it a versatile reagent for organic synthesis. It can be employed in the synthesis of various complex organic molecules, including those with potential applications in materials science, pharmaceuticals, and agrochemicals.
Used in Drug Design and Development:
(E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-bromoacrylic acid is used as a key intermediate in the design and development of novel drugs. Its unique combination of functional groups and physicochemical properties allows for the creation of drug candidates with improved potency, selectivity, and pharmacokinetic profiles.
Used in the Pharmaceutical Industry:
Within the pharmaceutical industry, (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-bromoacrylic acid is utilized as a starting material for the synthesis of new drug candidates. Its potential pharmacological activity and diverse biological properties make it a promising compound for the development of innovative therapeutics to address various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1642300-91-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,4,2,3,0 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1642300-91:
(9*1)+(8*6)+(7*4)+(6*2)+(5*3)+(4*0)+(3*0)+(2*9)+(1*1)=131
131 % 10 = 1
So 1642300-91-1 is a valid CAS Registry Number.
1642300-91-1Relevant articles and documents
NUCLEAR TRANSPORT MODULATORS AND USES THEREOF
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Paragraph 00336, (2015/01/07)
The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the compounds of formula (I) or their pharmaceutically acceptable salts, and methods of using said compounds, salts and compositions in the treatment of various disorders associated with CRM1 activity.
