16441-34-2

Usage

Uses

Used in Organic Synthesis:
(2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the formation of diverse chemical entities, contributing to the development of new materials and molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER is utilized as a starting material for the development of potential drug candidates. Its structural features may offer novel therapeutic opportunities, particularly in the areas of medicinal chemistry and drug discovery.
Used in Drug Development:
Due to its potential biological activities, (2-PHENYL-THIAZOL-4-YL)-ACETIC ACID ETHYL ESTER may be employed in drug development for the treatment of various diseases and conditions. Further research is necessary to explore its full potential and establish its efficacy and safety in clinical applications.

InChI:InChI=1/C13H13NO2S/c1-2-16-12(15)8-11-9-17-13(14-11)10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3

Upstream product

• 13176-46-0 4-bromoethyl acetoacetate 
• 2227-79-4 benzenecarbothioamide 
• 638-07-3 ethyl (2-chloroaceto)acetate 

Downstream Products

• 1009071-47-9 C₂₁H₂₄N₂O₃S₂ 
• 449780-22-7 methyl 2-(2-phenylthiazol-4-yl)acetate 
• 1613057-22-9 ethyl (2-phenylthiazol-4-yl)diazoacetate 
• 64483-96-1 2-(2-phenylthiazol-4-yl)ethan-1-ol 
• 645393-01-7 2-(2-phenylthiazol-4-yl)ethan-1-amine 

Relevant academic research and scientific papers

Synthesis and Antimicrobial Screening of 2-Aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives

A new series of 2-aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole derivatives was synthesized by condensation of 2-(2-substituted thiazol-4-yl)acetohydrazide with aryl aldehydes followed by oxidative cyclocondensation using iodobenzene diacetate. The

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

The parasitic trypanosomes Trypanosoma brucei and T. cruzi are responsible for significant human suffering in the form of human African trypanosomiasis (HAT) and Chagas disease. Drugs currently available to treat these neglected diseases leave much to be

Synthesis and Antifungal Screening of 2-(2-Aryl-4-methyl-thiazol-5-yl)-5-((2-aryl/benzylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives

(Chemical Equation Presented) A new series of synthesis and biological screening of 2-(2-aryl-4-methyl-thiazol-5-yl)-5-((2-aryl/benzylthiazol-4-yl)methyl)-1,3,4-oxadiazole derivatives 5a-i was achieved by condensation of 2-(2-aryl/benzylthiazol-4-yl)aceto

HETEROCYCLIC COMPOUNDS AND USE OF SAME

Novel heterocyclic compounds are provided which display useful efficacy in the treatment of diseases caused by trypanosomatids. Particularly, the compounds of the invention are useful in the treatment of HAT and/or Chagas disease and/or Animal African trypanosomiasis (AAT).

Development of new thiazole-based iridium catalysts and their applications in the asymmetric hydrogenation of trisubstituted olefins

New thiazole-based chiral N,P-ligands that are open-chain analogues of known cyclic thiazole ligands have been synthesized and evaluated in the iridium-catalyzed asymmetric hydrogenation of trisubstituted olefins. Chirality was introduced into the ligands through a highly diastereoselective alkylation using Oppolzer's camphorsultam as chiral auxiliary. In general, the new catalysts are as reactive and selective as their cyclic counterparts for the asymmetric hydrogenation of various trisubstituted olefins. This journal is The Royal Society of Chemistry.

IMIDAZO(1,2-a)PYRIDINE DERIVATIVE

A compound reprsented by the following formula (I), its salts or nsolvates thereof capable of specifically or selectively expressig an antifungal activity in a broad spectrum based on the novel mechanism thereof of 1,6-β-glucan synthesis inhibition, and an antifungal agent containing any of them.

1,2-disubstituted-6-oxo-3-phenyl-piperidine-3-carboxamides and combinatorial libraries thereof

The invention relates to combinatorial libraries containing two or more novel piperidine-3-carboxamide derivative compounds, methods of preparing the piperidine-3-carboxamide derivative compounds and piperidine-3-carboxamide derivative compounds bound to a resin

4H-pyrano[4,3-d]thiazole derivatives and process therefor

4H-Pyrano[4,3-d]thiazole derivatives characterized by having a 4H-pyrano[4,3-d]thiazole nucleus having a phenyl substituent at position 2 and a substituent at position 4, said substituent incorporating an acidic or basic function therein, are disclosed. T