16441-37-5Relevant academic research and scientific papers
Synthesis and Antifungal Screening of 2-(2-Aryl-4-methyl-thiazol-5-yl)-5-((2-aryl/benzylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives
Mhaske, Pravin C.,Shelke, Shivaji H.,Gadge, Kisan,Shinde, Abhijit
, p. 129 - 134 (2016)
(Chemical Equation Presented) A new series of synthesis and biological screening of 2-(2-aryl-4-methyl-thiazol-5-yl)-5-((2-aryl/benzylthiazol-4-yl)methyl)-1,3,4-oxadiazole derivatives 5a-i was achieved by condensation of 2-(2-aryl/benzylthiazol-4-yl)aceto
Synthesis and pharmacological evaluation of a novel series of 2-((2-aryl thiazol-4-yl)methyl)-5-(alkyl/alkylnitrile thio)-1,3,4-oxadiazole derivatives as possible antifungal agents
Shelke, Shivaji H.,Mhaske, Pravin C.,Kasam, Sridhar Kumar,Bobade, Vivek D.
, p. 1893 - 1897 (2014)
In the present investigation, a novel series of 2-[(2-arylthiazol-4-yl)methyl]-5-(alkyl/alkylnitrile thio)-1,3,4-oxadiazole derivatives were synthesized by cyclo-condensation of 2-(2-substituted thiazol-4-yl)aceto hydrazide with carbon disulfide followed by S-alkylation with alkyl halide in dry acetone. All the newly synthesized compounds were characterized by spectral (IR, 1H NMR, 13C NMR, mass, and elemental analysis) methods. The title compounds were screened for in vitro antifungal activity and most of the synthesized compounds show moderate to good antifungal activity.
Synthesis and Antimicrobial Screening of 2-Aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives
Mhaske, Pravin C.,Shelke, Shivaji H.,Bhoye, Manish,Bobade, Vivek D.
, p. 1590 - 1597 (2017/03/27)
A new series of 2-aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole derivatives was synthesized by condensation of 2-(2-substituted thiazol-4-yl)acetohydrazide with aryl aldehydes followed by oxidative cyclocondensation using iodobenzene diacetate. The
