164471-65-2Relevant academic research and scientific papers
Synthesis of Isocoumarins from o-Iodobenzoic Acid and Terminal Acetylenes Mediated by Palladium Complexes and Zinc Chloride
Liao, Hong-Yueh,Cheng, Chien-Hong
, p. 3711 - 3716 (1995)
o-Iodobenzoic acid (1) reacts with various terminal acetylenes (HCCR) in the presence of Pd(PPh3)4, Et3N, and ZnCl2 in DMF to give the corresponding 3-substituted isocoumarins (: R = n-C4H9 (2a); n-C3H7 (3a); CH2OCH3 (4a); C(CH3)2OH (5a); CH2OH (
