Synthesis of Isocoumarins from o-Iodobenzoic Acid and Terminal Acetylenes Mediated by Palladium Complexes and Zinc Chloride

DOI: 10.1021/jo00117a023

Source and publish data:

Journal of Organic Chemistry p. 3711 - 3716 (1995)

Update date:2022-08-04

Topics:

Authors:

Liao, Hong-Yueh

Cheng, Chien-Hong

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00117a023

o-Iodobenzoic acid (1) reacts with various terminal acetylenes (HCCR) in the presence of Pd(PPh3)4, Et3N, and ZnCl2 in DMF to give the corresponding 3-substituted isocoumarins (: R = n-C4H9 (2a); n-C3H7 (3a); CH2OCH3 (4a); C(CH3)2OH (5a); CH2OH (

Full text of DOI:10.1021/jo00117a023

Products guided by the article

Product name:1--4-(trimethylsilyl)-1,3-butadiyne

Cas No:164471-65-2

R&D Labs maybe for 164471-65-2

KindChem Co.,Ltd,

Contact:+86-25-85281586

Address:13F,Bld2#,South of Longpan Road
Laohekou Jinghong Chemical Co.,Ltd

Contact:+86-0710-3702747

Address:163.East，Huagong Road，Laohekou
zhuzhou zhongle chemical co. ltd.

Contact:+86-0731 28228409

Address:Zhuzhou, Hunan, China
MedicalChem(Yancheng)Manuf.Co.,Ltd.

Contact:+86-515-84383366

Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
BIOS CHEMICALS

Contact:+33-5-34012600

Address:28 ZA des Pignès

Relevant to this article

A,B-Diheteropentalenes by a Tandem Intramolecular Diels-Alder/Reverse Diels-Alder Reaction Sequence. Application to the Synthesis of Thieno<3,4-b>furan

Doi:10.1071/CH9950593
(1995)
Catalytic potentials of homodioxo-bimetallic dihydrazone complexes of uranium and molybdenum in a homogeneous oxidation of alkenes

Doi:10.1007/s00706-015-1477-9
(2015)
Synthesis of New Peptidyl Imidazodithi(and -thiadi)azoles as Potential Fungicides

Doi:10.1021/jf00057a038
(1995)
Synthesis of novel caspase inhibitors for characterization of the active caspase proteome in vitro and in vivo

Doi:10.1021/jm060385h
(2006)
Pallidium catalysed reactions of allenes, carbon monoxide and nucleophiles

Doi:10.1016/S0040-4020(98)00115-X
(1998)
Sulphur Extrusion. Part 4. A Halogen-catalysed Conversion of Thiocarbonyl Compounds into their Corresponding Oxygen Analogues using Alkoxides and Hydroxide

Doi:10.1039/P19810002647
(1981)

Article Doi