Synthesis of Isocoumarins from o-Iodobenzoic Acid and Terminal Acetylenes Mediated by Palladium Complexes and Zinc Chloride

DOI: 10.1021/jo00117a023

Source and publish data:

Journal of Organic Chemistry p. 3711 - 3716 (1995)

Update date:2022-08-04

Topics:

Authors:

Liao, Hong-Yueh

Cheng, Chien-Hong

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00117a023

o-Iodobenzoic acid (1) reacts with various terminal acetylenes (HCCR) in the presence of Pd(PPh3)4, Et3N, and ZnCl2 in DMF to give the corresponding 3-substituted isocoumarins (: R = n-C4H9 (2a); n-C3H7 (3a); CH2OCH3 (4a); C(CH3)2OH (5a); CH2OH (

Full text of DOI:10.1021/jo00117a023

Products guided by the article

Product name:1--4-(trimethylsilyl)-1,3-butadiyne

Cas No:164471-65-2

R&D Labs maybe for 164471-65-2

Suzhou Wedo Chemicals Co., Ltd.

Contact:86 512 58100425

Address:Zonger Road, DongSha Industry Park , Zhangjiagang, Jiangsu, China
Second Pharma Co., Ltd

Contact:+86-575-82733999 0575-82732999

Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province
Chemieliva Pharmaceutical Co., Ltd.

website:http://www.chemieliva.com

Contact:+86-23-67770219

Address:99 Longhua Road, Yubei District, 401147, Chongqing, China Email: sales@chemieliva.com Tel:0086-23-67770219 Fax: 0086-23-67770220 Attn: Andy Huang
Simagchem Corporation

website:http://www.simagchem.com

Contact:+86-592-2680277

Address:21/F Hualong Office Building,No.6 Hubin East Road, Xiamen,China
qingdao goldenchem imp and exp co.,ltd.

Contact:532-55579246

Address:no.62 ,haier road laoshan distirct

Relevant to this article

A,B-Diheteropentalenes by a Tandem Intramolecular Diels-Alder/Reverse Diels-Alder Reaction Sequence. Application to the Synthesis of Thieno<3,4-b>furan

Doi:10.1071/CH9950593
(1995)
Catalytic potentials of homodioxo-bimetallic dihydrazone complexes of uranium and molybdenum in a homogeneous oxidation of alkenes

Doi:10.1007/s00706-015-1477-9
(2015)
Synthesis of New Peptidyl Imidazodithi(and -thiadi)azoles as Potential Fungicides

Doi:10.1021/jf00057a038
(1995)
Synthesis of novel caspase inhibitors for characterization of the active caspase proteome in vitro and in vivo

Doi:10.1021/jm060385h
(2006)
Pallidium catalysed reactions of allenes, carbon monoxide and nucleophiles

Doi:10.1016/S0040-4020(98)00115-X
(1998)
Sulphur Extrusion. Part 4. A Halogen-catalysed Conversion of Thiocarbonyl Compounds into their Corresponding Oxygen Analogues using Alkoxides and Hydroxide

Doi:10.1039/P19810002647
(1981)

Article Doi