164513-49-9

Basic information

• Product Name: 2-bromo-1-(bromomethyl)-5-methoxy-3-methylbenzene
• Synonyms: 2-bromo-1-(bromomethyl)-5-methoxy-3-methylbenzene
• CAS NO: 164513-49-9
• Molecular Weight: 293.986
• Mol File: 164513-49-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-bromo-1-(bromomethyl)-5-methoxy-3-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1-(bromomethyl)-5-methoxy-3-methylbenzene(164513-49-9)
• EPA Substance Registry System: 2-bromo-1-(bromomethyl)-5-methoxy-3-methylbenzene(164513-49-9)

Safety Data

• Hazardous Substances Data: 164513-49-9(Hazardous Substances Data)

Upstream product

• 874-63-5 3,5-dimethylmethoxybenzene 
• 6267-34-1 2-bromo-5-methoxy-1,3-dimethyl-benzene 
• 108-68-9 3,5-Dimethylphenol 

Downstream Products

• 153763-95-2 2-bromo-1,3-bis(bromomethyl)-5-methoxybenzene 
• 110451-90-6 (2-bromo-5-methoxy-3-methylphenyl)methanol 
• 202195-07-1 3-methoxy-5-methyl-2-(1,4,5-trimethoxynaphthalen-2-yl)benzaldehyde 
• 199612-65-2 2-iodo-3-methoxy-5-methylbenzaldehyde 
• 119650-45-2 (2-iodo-3-methoxy-5-methylphenyl)methanol 
• 119650-44-1 (3-methoxy-5-methylphenyl)methanol 
• 207287-39-6 (S)-2-(2-Bromo-5-methoxy-3-methyl-phenyl)-4-isopropyl-4,5-dihydro-oxazole 
• 294872-87-0 methyl 3-[2-(cyanomethyl)-4-methoxy-6-methylphenyl]propionate 
• 198274-51-0 methyl 3-{4-methoxy-2-[(methoxycarbonyl)methyl]-6-methylphenyl}propionate 
• 198274-49-6 ethyl (E)-3-[2-(cyanomethyl)-4-methoxy-6-methylphenyl]acrylate 
• 294872-90-5 3-[2-(carboxymethyl)-4-methoxy-6-methylphenyl]propionic acid 

Relevant articles and documents

Regioselectivity in free radical bromination of unsymmetrical dimethylated pyridines

During a literature review some curious inconsistencies in the free radical bromination of picolines were noted. To achieve a better understanding of the mechanisms and regioselectivity we reran these reactions, extending our work to unsymmetrical lutidin

New 2,2′-substituted 4,4′-dimethoxy-6,6′-dimethyl[1, 1′-biphenyls], inducing a strong helical twisting power in liquid crystals

Based on the stabilisation of the molecular motion by the chiral residue, novel optically active biphenylic chiral dopants for nematic liquid crystals were developed. This molecular congestion was obtained by introducing mesogenic residues on the 2,2′-positions of the chiral biphenyl; this led to a novel molecular architecture that was found to be efficient. The synthesised optically active biphenyls were characterised with very short cholesteric pitches when used as chiral dopants in nematic liquid crystals. The synthesis of the enatiomerically pure biphenyl dopants and their preliminary physicochemical characterisations are described.

Decagram-Scale Synthesis of the Neocarzinostatin Carboxylic Acid

Neocarzinostatin carboxylic acid (2) was synthesized on a 10-g scale in 9 steps and 43% overall yield from 3,5-dimethylanisol (9) (Schemes 5, 7). The hindered bromoarene 23, reached after 3 steps, underwent a high-temperature Heck coupling with ethyl acry