294872-87-0Relevant academic research and scientific papers
Decagram-Scale Synthesis of the Neocarzinostatin Carboxylic Acid
Goerth, Felix Christian,Rucker, Mark,Eckhardt, Matthias,Brueckner, Reinhard
, p. 2605 - 2612 (2007/10/03)
Neocarzinostatin carboxylic acid (2) was synthesized on a 10-g scale in 9 steps and 43% overall yield from 3,5-dimethylanisol (9) (Schemes 5, 7). The hindered bromoarene 23, reached after 3 steps, underwent a high-temperature Heck coupling with ethyl acry
