164527-43-9Relevant academic research and scientific papers
Copper-Catalyzed Perfluoroalkylation of Allyl Phosphates with Stable Perfluoroalkylzinc Reagents
Liu, Lihua,Bao, Xifei,Xiao, Hua,Li, Junlan,Ye, Feifan,Wang, Chaoqin,Cai, Qinhua,Fan, Shilu
, p. 423 - 434 (2019/01/08)
A general and practical method for copper-catalyzed cross-coupling of allyl phosphates with stable perfluoroalkylzinc reagents has been developed. The reaction proceeds under mild reaction conditions with high efficiency, good functional group tolerance, and high regio- A nd stereoselectivities and provides general, straightforward, and useful access to allyl-perfluoroalkyl compounds. Preliminary mechanistic studies reveal that the allyl copper intermediate may be involved in the catalytic cycle.
Synthesis of β-substituted α-amino acids with use of iridium-catalyzed asymmetric allylic substitution
Kanayama, Takatoshi,Yoshida, Kazumasa,Miyabe, Hideto,Kimachi, Tetsutaro,Takemoto, Yoshiji
, p. 6197 - 6201 (2007/10/03)
The asymmetric synthesis of β-substituted α-amino acids with use of iridium-catalyzed allylic substitution was described. The Ir-catalyzed allylic substitution of diphenylimino glycinate with allylic phosphates proceeded smoothly even at 0 °C and gave branch products with high enantioselectivity (up to 97% ee), when chiral bidentate phosphite bearing the 2-ethylthioethyl group was employed. In addition, both diastereomers of the branch products were synthesized stereoselectively by simply switching the base employed. These methods were also applied to the asymmetric synthesis of quaternary α-amino acids.
Chirale Phosphanodihydrooxazole in der asymmetrischen Katalyse: Wolfram-katalysierte allylische Substitution
Lloyd-Jones, Guy C.,Pfaltz, Andreas
, p. 534 - 536 (2007/10/02)
Stichworte: Alkylierungen * Asymmetrische Synthesen * Dihydrooxazole * Katalyse * Wolframverbindungen
