164593-05-9

Basic information

• Product Name: 2-(2,6-DIFLUOROPHENYL)-1H-1,3-BENZODIAZOLE
• Synonyms: 2-(2,6-DIFLUOROPHENYL)-1H-1,3-BENZODIAZOLE;2-(2,6-DIFLUOROPHENYL)-1H-BENZIMIDAZOLE
• CAS NO: 164593-05-9
• Molecular Formula: C₁₃H₈F₂N₂
• Molecular Weight: 230.216
• Mol File: 164593-05-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 202 °C
• Boiling Point: 390.6±52.0 °C(Predicted)
• Appearance: /
• Density: 1.363±0.06 g/cm3(Predicted)
• PKA: 10.69±0.10(Predicted)
• CAS DataBase Reference: 2-(2,6-DIFLUOROPHENYL)-1H-1,3-BENZODIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,6-DIFLUOROPHENYL)-1H-1,3-BENZODIAZOLE(164593-05-9)
• EPA Substance Registry System: 2-(2,6-DIFLUOROPHENYL)-1H-1,3-BENZODIAZOLE(164593-05-9)

Safety Data

• Hazardous Substances Data: 164593-05-9(Hazardous Substances Data)

Usage

General Description

2-(2,6-DIFLUOROPHENYL)-1H-1,3-BENZODIAZOLE is a chemical compound with the molecular formula C15H9F2N. It is a benzodiazole derivative that contains two fluorine atoms attached to a phenyl ring. 2-(2,6-DIFLUOROPHENYL)-1H-1,3-BENZODIAZOLE has been studied for its potential use in pharmaceuticals, particularly in the development of new drugs for various medical conditions. It is also used in research as a fluorescent probe for studying cellular processes. 2-(2,6-DIFLUOROPHENYL)-1H-1,3-BENZODIAZOLE is considered a valuable building block in organic synthesis and has potential applications in materials science and biochemistry.

Upstream product

• 437-81-0 2,6-difluorobenzaldehyde 
• 4403-69-4 2-amino-1-benzylamine 
• 85118-00-9 2,6-Difluorobenzyl bromide 
• 95-54-5 1,2-diamino-benzene 
• 18063-02-0 2,6-difluorobenzoylchloride 
• 88-74-4 2-nitro-aniline 
• 385-00-2 2,6-difluorobenzoic acid 
• 199594-48-4 2,6-difluoro-N-(2-nitrophenyl)benzamide 

Downstream Products

• 1015084-74-8 [CoCl₂(2-(2,6-difluorophenyl)-1H-benzimidazole)2] 
• 199594-59-7 1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)benzoimidazole 
• 199594-60-0 1-benzyl-2-(2,6-difluorophenyl)benzimidazole 

Relevant articles and documents

POLYMERIC ANION-CONDUCTING MEMBRANE

The present invention provides compounds, especially polymeric compounds, having at least one imidazole and/or imidazolium structural unit, a process for preparation thereof and for the use thereof.

Synthesis of benzimidazoles by copper-catalyzed aerobic oxidative domino reaction of 1,2-diaminoarenes and arylmethyl halides

Arylmethyl halides are readily synthesized via halogenation from the basic raw materials, even in green processes. They are used to replace their downstream products to prepare medicinally important 2-aryl benzimidazoles. CuBr-catalyzed synthesis of 2-aryl benzimidazoles from arylmethyl halides and 1,2-diaminoarenes via a one-pot domino reaction is developed. This new synthetic method is simple, practical and cost saving, and tolerates wide functional groups. A mechanism of CuBr-catalyzed aerobic oxidative domino reaction via a one-pot four-step process is proposed.

Microwave-assisted one step high-throughput synthesis of benzimidazoles

One-pot synthesis of benzimidazoles from diamines and carboxylic acids was developed under microwave irradiation condition, which provided a practical and efficient method for high-throughput synthesis of this important class of heterocyclic compounds.