16475-85-7

Usage

Preparation

Preparation by cyclization of 1,1,3,3-tetraacetylpropene (formerly so called methenylbisacetylacetone) (SM) (m.p. 117–118°) , ? by adding a solution of SM (1 mol) in benzene to a sodium methoxide (4 mol) or magnesium methoxide (4 mol) solution in methanol and set aside for 24 h (quantitative yields) ; ? on heating of its potassium salt in alcoholic solution for 6–8 h at reflux. SM was prepared by treatment of ethoxymethyleneacetylacetone (m.p. 140–142°) with the potassium salt of acetylacetone in ethanol.

Upstream product

• 4110-55-8 3,5-diacetylheptane-2,6-dione 
• 31517-59-6 4,6-diacetyl-3-methyl-cyclohex-2-enone 
• 33884-41-2 ethoxylideneacetylacetone 
• 15435-71-9 sodium acetylacetonate 
• 71043-43-1 1,1'-(2-hydroxy-2,6-dimethyl-2H-pyran-3,5-diyl)-bis-ethanone 
• 30561-07-0 5-nitro-2,4-dimethoxypyrimidine 
• 123-54-6 acetylacetone 
• 122-46-3 3-acetoxytoluene 
• 54283-20-4 1,1,2,2-Tetraacetylcyclopropane 
• 68541-87-7 1-(2-methyl-5-nitropyridin-3-yl)ethanone 
• 90860-45-0 4-methoxy-6-methyl-5-nitropyrimidine 
• 14080-32-1 5-nitropyrimidine 
• 15579-58-5 5-nitro-4-methoxypyrimidine 
• 67-66-3 chloroform 

Downstream Products

• 131941-98-5 (E)-1-{2-Hydroxy-5-[(E)-3-(4-methoxy-phenyl)-acryloyl]-4-methyl-phenyl}-3-(4-methoxy-phenyl)-propenone 
• 108-39-4 3-methyl-phenol 
• 131942-01-3 (E)-1-{4-Hydroxy-5-[5-(4-methoxy-phenyl)-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl]-2-methyl-phenyl}-3-(4-methoxy-phenyl)-propenone 
• 131941-99-6 2-(4-Methoxy-phenyl)-6-[(E)-3-(4-methoxy-phenyl)-acryloyl]-7-methyl-chromen-4-one 

Relevant academic research and scientific papers

Copper-catalyzed synthesis of phenolic compounds with DMSO as the methylene source

The application of DMSO as an ideal source of carbon is highly attractive. A simple and novel protocol has been developed for the synthesis of phenolic compounds via CuSO4·5H2O-catalyzed cyclization of 1,3-dicarbonyl compounds with DMSO. It was found that the unsymmetrical 1,3-dicarbonyl compounds always gave a mixture of two isomeric products. In addition, the deuterium-labeling experiments revealed that the C2 in benzene rings resulted from DMSO.

Preparation method of multi-substituted phenol

The invention relates to a preparation method of multi-substituted phenol. A compound of the multi-substituted phenol has a structure as shown in a formula III, and is prepared by the reaction of acetylacetone and carbon tribromide, wherein alkali in the

Palladium-catalyzed formation of phenolic compounds by reaction of carbonyl compounds with carbon dioxide

The use of carbon dioxide as a renewable and environmentally friendly source of carbon is highly attractive. A novel and efficient protocol for the synthesis of phenolic compounds from carbonyl compounds and carbon dioxide in the presence of a catalytic amount of Pd(OAc)2 has been developed. This reaction is appealing for industries and is a tool for the sequestration of carbon dioxide.

Homoconjugation and transannular orbital interactions detected by photoelectron and13C-NMR spectroscopy. Bicyclo[3.3.1]nona-3,7-diene-2,6-dione and bicyclo[3.3.1]nonane-2,6-dione

Transannular orbital interactions between two ketone carbonyl groups located at positions 2 and 6 on the bicyclo[3.3.1]nonane carbocyclic framework were detected by 13C-NMR and photoelectron spectroscopy (PES). Thus, an ～4.4-ppm shielding of th

PYRIMIDINE SIGMA-COMPLEXES. 7. THE RECYCLIZATION OF 5-NITROPYRIMIDINE AND ITS METHOXY DERIVATIVES UPON REACTION WITH THE ACETYLACETONE CARBANION

A study was carried out on the reaction of 5-nitro and 5-nitromethoxypyrimidines with the acetylacetone carbanion.Benzene and pyridine derivatives are formed as a result of recyclization.The direction of the reaction depends on the position of the substituents in the pyrimidine ring and the nature of the bases.

1,1,2,2-TETRAACETYLCYCLOPROPANE: A VERSATILE SOURCE OF HETEROCYCLIC AND HOMOCYCLIC DERIVATIVES

1,1,2,2-Tetraacetylcyclopropane, 2, obtained in high yield from tetraacetylethylene 1, and diazomethane, gives rise to oxabicyclohexane derivatives 4a and 4c, halogenated dihydrofuran 10, polycyclic derivatives 13a and 14 and bicyclohexanes