164916-44-3Relevant articles and documents
In situ generation of the coates catalyst: A practical and versatile catalytic system for the carbonylation of meso-epoxides
Ganji, Prasad,Doyle, David J.,Ibrahim, Hasim
, p. 3142 - 3145 (2011)
A highly active catalytic system for the carbonylation of meso- and terminal epoxides to β-lactones is described. The active catalyst, analogous to Coates' catalyst, is generated in situ from commercially available (TPP)CrCl and Co2(CO)8/
Asymmetric synthesis of the cis- And trans-stereoisomers of 4-aminopyrrolidine-3-carboxylic acid and 4-aminotetrahydrofuran-3-carboxylic acid
Bunnage, Mark E.,Davies, Stephen G.,Roberts, Paul M.,Smith, Andrew D.,Withey, Jonathan M.
, p. 2763 - 2776 (2007/10/03)
The diastereoselective conjugate addition of lithium (S)-N-benzyl-N- α-methylbenzylamide has been successfully applied to the first asymmetric syntheses of cis-(3S,4R)- and fraBs-(3R,4R)-4-arninotetrahydrofuran-3-carboxylic acids (26% and 25% overall yield respectively, >98% d.e. and >97% e.e. in each case). Furthermore, the most efficient asymmetric synthesis to date of cis-(3R,4R)- and trans-(3R,4S)-4-aminopyrrolidine carboxylic acids is delineated: for cis-(3R,4R), four steps, >98% d.e., 52% overall yield; for trans-(3R,4S), five steps, >98% d.e., 50% overall yield.
