164979-75-3Relevant academic research and scientific papers
Remarkably mild and simple preparation of sulfenate anions from β-sulfinylesters: A new route to enantioenriched sulfoxides
Caupene, Caroline,Boudou, Cedric,Perrio, Stephane,Metzner, Patrick
, p. 2812 - 2815 (2007/10/03)
(Chemical Equation Presented) A general, efficient, and experimentally simple method for the generation of sulfenate salts has been developed using β-sulfmylesters as substrates. The process is based on a retro-Michael reaction, initiated by deprotonation at low temperature. Upon treatment with alkyl halides, the liberated sulfenates are subsequently converted into sulfoxides in good to excellent yield. Extension of the methodology to an unprecedented access to nonracemic sulfoxides by introduction of an enantiopure ligand, (-)-sparteine, is also described.
Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene active on the cardiovascular system
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, (2008/06/13)
Compounds of the formula: STR1 wherein R is a hydrogen atom or an OY group; R1 is a hydrogen atom or in OY' group; R2 is a hydrogen atom or an OY" group; provided that at lent one among R, R1 and R2 is hydrogen
