165059-45-0Relevant academic research and scientific papers
A tandem isomerization/prins strategy: Iridium(III)/Bronsted acid cooperative catalysis
Lombardo, Vince M.,Thomas, Christopher D.,Scheidt, Karl A.
, p. 12910 - 12914 (2013)
Working together: A mild and efficient isomerization/protonation sequence generates pyran-fused indoles by cooperative catalysis between cationic iridium(III) and Bi(OTf)3. Three distinct cyclization manifolds lead to the corresponding bioactive scaffolds in good yields. In addition, N-substituted indoles can be synthesized enantioselectively in the presence of a chiral phosphate. Copyright
A concise synthesis of carpanone using solid-supported reagents and scavengers
Baxendale, Ian R.,Lee, Ai-Lan,Ley, Steven V.
, p. 1850 - 1857 (2007/10/03)
The synthesis of the natural product carpanone by utilization of polymer supported reagents, eliminating the need for conventional purification techniques was reported. The synthesis and crystal structure of a polymer-supported iridium catalyst for isomerization was also reported. The observations showed that isomerization of electron-rich aromatic compounds by the catalyst resulted in products with predominantly trans alkene geometry. However, the electron-poor derivatives were found to be less prone to rearrangement.
