16522-41-1

Usage

InChI:InChI=1/C10H9NO4/c1-7(2)10(12)15-9-5-3-8(4-6-9)11(13)14/h3-6H,1H2,2H3

Upstream product

• 100-02-7 4-nitro-phenol 
• 920-46-7 Methacryloyl chloride 
• 463-49-0 1,2-propanediene 
• 201230-82-2 carbon monoxide 
• 79-41-4 poly(methacrylic acid) 
• 814-68-6 acryloyl chloride 

Downstream Products

• 893445-27-7 S-p-nitrophenyl 2-methylpropanethioate 
• 54667-28-6 S-phenyl 2-methylpropenethioate 

Relevant academic research and scientific papers

Control of the Alternating Sequence for N-Isopropylacrylamide (NIPAM) and Methacrylic Acid Units in a Copolymer by Cyclopolymerization and Transformation of the Cyclopendant Group

An alternating copolymer of methacrylic acid and N-isopropyl acrylamide (NIPAM) was synthesized by selective cyclopolymerization of a special divinyl monomer and transformation of repeating cyclo-units in the resultant cyclopolymer. Crucial to the breakthrough is the monomer design in view of two types of cleavable bonds (3° ester and activated ester) in the pendant group of the monomer and the lower reactivity ratio of the two double bonds (methacrylate and electron-poor acrylate) for the polymerizable groups. The thus-obtained cyclopolymer was transformed into the alternating copolymer by transformation of the activated ester into amide by isopropyl amine and cleavage of the 3° ester by trifluoroacetic acid. The resultant copolymer showed thermal and pH response in aqueous solution that was different from the 1:1 random copolymer as well as the homopolymers.

Smart hydrogels co-switched by hydrogen bonds and π-π stacking for continuously regulated controlledrelease system

A series of hydrogels with continuously regulatable release behavior can be achieved by incorporating hydrogen bonding and π-π stacking co-switches in polymers. A poly(nitrophenyl methacrylate-co-methacrylic acid) hydrogel (NPMAAHC) for control over drug

Isothiourea-catalysed transfer hydrogenation of α,β-unsaturated para-nitrophenyl esters

A protocol for the isothiourea-catalysed transfer hydrogenation of α,β-unsaturated para-nitrophenyl esters using Hantzsch ester has been developed. Good to excellent yields are observed using α,β-unsaturated aryl esters bearing electron-withdrawing β-subs

PH-responsive nano-drug delivery system and preparation method thereof

A pH-responsive nano-drug delivery vehicle is a synthetic block polymer P(ALD)-g-DOX-b-P(PEG)-b-PBA-VI, p-nitrophenol is substituted by p-hydroxybenzaldehyde through transesterification reaction, andan aldehyde group is effectively prevented from being ox

Synthesis, characterization and reactivity ratios of co-polymers derived from 4-nitrophenyl methacrylate and butyl methacrylate

Poly (NPNA) has been synthesized from 4-nitrophenylmethacrylate (NPMA) in 2-butanone using BPO as a free radical initiator. Copolymers of NPMA and BMA [poly(NPMA-co-BMA)] have also likewise been obtained. The polymers have been characterized by IR, 1

Pallidium catalysed reactions of allenes, carbon monoxide and nucleophiles

Hydridopalladium(II) species generated in situ by oxidative addition of Pd(0) to acetic acid or acidic hydroxyl substrates (phenols, oximes) catalyse the termolecular assembly of allenes, CO and amines (primary, secondary) or oxygen nucleophiles to give methacrylamides or methacrylate esters and derivatives thereof in good to excellent yield.