16523-02-7

Basic information

• Product Name: 2-BROMOETYL-METHYLSULFONE
• Synonyms: 2-BROMOETYL-METHYLSULFONE;2-BroMoethyl Methyl Sulfone;1-BroMo-2-(Methylsulfonyl)-ethane
• CAS NO: 16523-02-7
• Molecular Formula: C₃H₇BrO₂S
• Molecular Weight: 187.06
• Mol File: 16523-02-7.mol

Chemical Properties

• Boiling Point: 126-128 °C(Press: 3.5 Torr)
• Appearance: /
• Density: 1.666±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-BROMOETYL-METHYLSULFONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOETYL-METHYLSULFONE(16523-02-7)
• EPA Substance Registry System: 2-BROMOETYL-METHYLSULFONE(16523-02-7)

Safety Data

• Hazardous Substances Data: 16523-02-7(Hazardous Substances Data)

Usage

Uses

Used in Electrochemical Applications:
2-BROMOETYL-METHYLSULFONE is used as a reagent for the preparation of sulfone-functionalized imidazolium ionic liquid electrolytes. These electrolytes exhibit interesting electrochemical properties, making them suitable for use in various electrochemical devices and systems.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-BROMOETYL-METHYLSULFONE is utilized as a building block or intermediate in the synthesis of a wide range of chemical compounds. Its unique structure allows it to participate in various chemical reactions, contributing to the formation of desired products.
Used in Pharmaceutical Industry:
2-BROMOETYL-METHYLSULFONE may also find applications in the pharmaceutical industry, where it can be used as a starting material or intermediate in the synthesis of drug candidates. Its chemical properties can be harnessed to develop new drugs with potential therapeutic benefits.
Used in Material Science:
In the realm of material science, 2-BROMOETYL-METHYLSULFONE can be employed in the development of novel materials with specific properties. Its incorporation into polymers or other materials can lead to the creation of materials with improved characteristics, such as enhanced stability, solubility, or reactivity.
Overall, 2-BROMOETYL-METHYLSULFONE is a versatile reagent with a broad range of applications across different industries, including electrochemistry, chemical synthesis, pharmaceuticals, and material science. Its unique structure and chemical properties make it a valuable component in the development of new technologies and products.

Upstream product

• 54187-93-8 1-bromo-2-(methylsulphanyl)ethane 
• 15205-66-0 2-(methylsulfonyl)ethyl alcohol 

Downstream Products

• 1056940-76-1 1-(2-(methylsulfonyl)ethyl)-4-(4-nitrophenyl)piperazine 
• 1625669-67-1 4-(3-(2-(methylsulfonyl)ethyl)-2,5-dioxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)benzonitrile 
• 1431872-15-9 C₂₄H₂₈N₆O₆S₂ 
• 1431874-72-4 C₂₁H₂₁FN₆O₄S 
• 1431872-13-7 C₂₄H₂₇FN₆O₆S₂ 
• 1431872-14-8 C₂₇H₃₀FN₉O₆S₂ 
• 1194373-79-9 4-[(2-fluoro-4-methylphenyl)amino]-7-methoxy-6-{4-[2-(methylsulfonyl)ethyl]piperazin-1-yl} cinnoline-3-carboxamide 

Relevant articles and documents

Synthesis and electrochemical property of sulfone-functionalized imidazolium ionic liquid electrolytes

Sulfone-functionalized imidazolium ionic liquids were synthesized from direct nucleophilic substitution for the first time. Detailed NMR analysis of the products revealed the competition pathways of classic SN2 substitution and E2 elimination i

Compound, liquid crystal composition, liquid crystal display element and liquid crystal display

The present invention relates to a compound, a liquid crystal composition, a liquid crystal display element, and a liquid crystal display. The compound is a compound represented by a formula I shown in the description. The liquid crystal composition of the present invention contains the compound represented by the formula I. The compound represented by the formula I has the advantages of good mutual solubility with other compounds and good UV resistance. As a reactive mesogen (RM), the compound has the advantages of good mutual solubility, high polymerization activity (less monomer residue), and strong binding ability. The compound can not only be used as a self-aligning agent for the liquid crystal compositions alone, but also can be used as a vertical alignment material for copolymerization with other RMs so as to be used as a self-aligning agent for the liquid crystal compositions in a PSA (polymer-supported alignment) and PS (polymer-stabilized) mode, the PI preparation process canbe avoided, the preparation process of the liquid crystal display element or liquid crystal display can be simplified, and the production efficiency can be improved.

Compounds, liquid crystal composition, liquid crystal display element and liquid crystal display

The invention relates to compounds, a liquid crystal composition, a liquid crystal display element and a liquid crystal display. The compounds are represented by a formula I shown in the description.The liquid crystal composition provided by the invention

2 - (amino) ethyl methyl sulphone salt and wherein the intermediate preparation method

The invention discloses a preparation method of a 2-(amino)ethyl methyl sulfone salt represented by formula 1. The preparation method comprises: (1) in an organic solvent and under the action of a substitution reaction catalyst, a compound 3 is reacted with a compound 4; and X is a halogen, and M is an alkali metal or an alkaline earth metal; and (2) a compound 2 prepared by the step (1) is reacted with an acidic aqueous solution to obtain a compound 1; n is equal to 1 or 2; m is equal to 1 or 2; and HmA is an organic acid or an inorganic acid. The invention also discloses a preparation method of the compound 2. The preparation method of the compound 2 comprises: 1) in an organic solvent and under the action of an alkali, a compound 5 is reacted with a halogenation reagent; and 2) in the organic solvent, under the action of the substitution reaction catalyst, the compound 4 is reacted with the compound 3 prepared by the step 1), X is a halogen, and M is an alkali metal or an alkaline earth metal. The preparation methods have low cost and easy availability of raw materials, have no environmental pollution factors, and are suitable for industrial mass production.

ARYLOXYACETYLINDOLES AND ANALOGS AS ANTIBIOTIC TOLERANCE INHIBITORS

The disclosure provides compounds and pharmaceutical compositions of aryloxyacetylindoles compounds and analogs useful for treating chronic and acute bacterial infections. Certain of the compounds are compounds of general Formula (I) (I) or a pharmaceutically acceptable salt or prodrug thereof. Certain compounds of this disclosure are MvfR inhibitors. MvfR inhibitors reduce the formation of antibiotic tolerant bacterial strains and are useful for treating Gram-negative bacterial infections and reducing the virulence of Pseudomonas aeruginosa. Methods of treating bacterial infections in a subject, including Pseudomonas aeruginosa infections, are also provided by the disclosure.

HETEROCYCLIC COMPOUNDS AND USES THEREOF

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder, a cancer, a tumor, an inflammatory disease, an autoimmune disease, psoriasis, dry eye or an immunologically related disease, and in some embodiments diseases or disorders related to the dysregulation of kinase such as, but not limited to, EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, FLT3(D835Y), ITK, TEC, TXK, BTK, or JAK, and the respective pathways.