15205-66-0

Basic information

• Product Name: 2-(METHYLSULFONYL)ETHANOL
• Synonyms: 2-(Methylsulfonyl)ethanol,2-Hydroxyethyl methyl sulfone;2-(Methylsulfonyl)ethanol, 98% 10GR;Ethanol, 2-(methylsulfonyl)-;hydroxyethyl;hydroxyethylmethylsulfone;2-(METHYLSULFONYL)ETHANOL;2-(METHANESULFONYL)ETHANOL;2-(METHANESULPHONYL)ETHANOL
• CAS NO: 15205-66-0
• Molecular Formula: C₃H₈O₃S
• Molecular Weight: 124.16
• EINECS: 239-261-2
• Product Categories: Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfones;Sulfur Compounds
• Mol File: 15205-66-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 31-33 °C(lit.)
• Boiling Point: 148-149 °C(lit.)
• Flash Point: >230 °F
• Appearance: /solid
• Density: 1.33
• Vapor Pressure: 4.16E-06mmHg at 25°C
• Refractive Index: 1.478-1.48
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• PKA: 13.61±0.10(Predicted)
• Water Solubility: Soluble in water.
• BRN: 1746915
• CAS DataBase Reference: 2-(METHYLSULFONYL)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(METHYLSULFONYL)ETHANOL(15205-66-0)
• EPA Substance Registry System: 2-(METHYLSULFONYL)ETHANOL(15205-66-0)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3-9
• Hazardous Substances Data: 15205-66-0(Hazardous Substances Data)

Usage

Uses

2-(Methylsulfonyl)ethanol may be used as reagent in the synthesis of phenols from aryl fluorides. It may be used in the preparation of 2-(methylsulfonyl)ethyl N,N-bis(2-chloroethyl)phosphorodiamidate. 2-Hydroxyethyl Methyl Sulfone, is the versatile building block used in the synthesis of more complex sulfur containing compounds. It can be used for the studies of inhibitor and substrate moieties to acetylcholinesterase.

General Description

Reaction of 2-(methylsulfonyl)ethanol with cotton cellulose yields methylsulfonylethyl substituents in the 2-O- to 6-O-positions of the monosubstituted D-glucopyranosyl unit of cotton cellulose.

InChI:InChI=1/C3H8O3S/c1-7(5,6)3-2-4/h4H,2-3H2,1H3

Upstream product

• 5271-38-5 2-methylmercapto-ethanol 
• 92543-10-7 2-(methylsulfonyl)ethyl acetate 
• 75-21-8 oxirane 
• 124-63-0 methanesulfonyl chloride 
• 83936-32-7 5-<<2-(methylsulfonyl)ethyl>thio>-1-(4-sulfamoylphenyl)-1,2,3,4-tetrazole 
• 50890-51-2 2-chloroethyl methyl sulfone 
• 94820-46-9 4-[4-(2-Methanesulfonyl-ethyl)-5-thioxo-4,5-dihydro-tetrazol-1-yl]-benzenesulfonamide 

Downstream Products

• 53298-29-6 2-methylsulfonyl ethyloxycarbonyl chloride 
• 91290-08-3 2-(methylsulfonyl)ethyl phosphorodichloridate 
• 299181-69-4 4-hydroxy-3-(morpholine-4-sulfonyl)-benzoic acid 
• 1243310-60-2 methyl 2,3,6-tri-O-benzyl-4-O-2-(methylsulfonyl)ethoxymethyl-α-D-glucopyranoside 
• 82206-48-2 methyl 2,3-di-O-benzyl-4,6-O-methylidene-α-D-glucopyranoside 
• 191604-52-1 2-methylsulfonylethyl methanesulfonate 
• 3680-02-2 methyl ethenyl sulphone 
• 1402797-76-5 (4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-3-((2-(4-hydroxy-2-methoxy-5-nitrophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)-4-methyloxazolidin-2-one 
• 53298-30-9 2-(methylsulfonyl) ethyl-4-nitrophenyl carbonate 
• 99180-10-6 4-bromo-benzenesulfonic acid-(2-methanesulfonyl-ethyl ester) 
• 98954-82-6 1-benzenesulfonyloxy-2-methanesulfonyl-ethane 
• 50890-51-2 2-chloroethyl methyl sulfone 

Relevant articles and documents

Sandwich type polyoxometalates encapsulated into the mesoporous material: Synthesis, characterization and catalytic application in the selective oxidation of sulfides

The A-type sandwich polyoxometalates of [(HOSnIVOH)3(PW9O34)2]12- (P2W18Sn3) and [(OCeIVO)3(PW9O34)2]12- (P2W18Ce3) were immobilized for the first time into the porous metal-organic framework MIL-101(Cr). FT-IR, powder X-ray diffraction, SEM-EDX, ICP analysis, N2 adsorption and thermogravimetric analysis collectively confirmed immobilization and good distribution of polyoxometalates into cages of MIL-101(Cr). The catalytic activities of the homogeneous P2W18Sn3 and P2W18Ce3 and the corresponding heterogeneous catalysts were examined in the oxidation of sulfides to sulfones with H2O2 as the oxidant at room temperature. The effects of different dosages of polyoxometalates, type of solvent, reaction time, amount of catalyst and oxidant in this catalytic system were investigated. The new P2W18Sn3@MIL-101 and P2W18Ce3@MIL-101 nanocomposites exhibited good recyclability and reusability in at least five consecutive reaction cycles without significant loss of activity or selectivity.

Immobilized Sandwich-Type Polyoxometalates [Mn4(XW9O34)2]n? on Tb-Doped TiO2 Nanoparticles as Efficient and Selective Catalysts in the Oxidation of Sulfides and Alcohols

Abstract: Sandwich-type polyoxometalates of [M4(XW9O34)2]n?(M = Mn2+, Cu2+, Zn2+, X = Ge4+, P5+, As5+) supported on Ln-doped TiO2(Ln = Nd3+, Sm3+, Tb3+and Dy3+) nanoparticles were prepared and their catalytic activities examined for oxidation of sulfides and alcohols. Results show that the catalytic activities of new nanocomposites were significantly higher than homogeneous conditions with corresponding sandwich-type polyoxometalates. The best results obtained by [Mn4(XW9O34)2]10?(X = P5+, As5+) supported on Tb/TiO2which were characterized by various techniques. The catalysts can be easily recovered and reused for at least five times without obvious decrease of catalytic activities and the structures of the catalysts remain unchanged after recycling and the yields for catalyst recovery are all above 95%. Graphical Abstract: [Figure not available: see fulltext.]