165283-75-0

Upstream product

• 50-00-0 formaldehyd 
• 70398-84-4 1,2-Bisbenzene 
• 17534-15-5 Benzene-1,2-dithiol 
• 95-50-1 1,2-dichloro-benzene 
• 911649-50-8 2,3-di(isopropylmercapto)benzoic acid chloride 
• 85686-14-2 2,3-bis(isopropylsulfanyl)benzoic acid 
• 544481-24-5 2,3-bis-isopropylsulfanyl-benzoic acid isopropyl ester 
• 165283-85-2 2,3-bis(isopropylmercapto)benzaldehyde 

Downstream Products

• 165283-76-1 2,3-bis(isopropylthio)benzyl chloride 
• 433288-22-3 1,2-bis[2,3-di(isopropylmercapto)phenyl]ethane 
• 165283-78-3 2,3-bis(isopropylthio)phenethyl amine 
• 165283-77-2 2,3-bis(isopropylthio)benzyl cyanide 
• 165283-80-7 3-<2-ethyl>-1,2-benzenedithiol 
• 165283-79-4 2,3-bis(isopropylthio)-1-[2-(N-tert-butoxycarbonylamino)ethyl]benzene 
• 332101-38-9 2-[2,3-bis(isopropylthio)benzyl]pyrimidine 
• 332101-34-5 2-[2,3-bis(isopropylthio)benzyl]pyridine 
• 433288-20-1 2,3-di(isopropylmercapto)benzyl bromide 

Relevant academic research and scientific papers

EFFICIENT SYNTHESIS AND BIOLOGICAL PROPERTIES OF NEW BENZOPENTATHIEPINS

New 6,7-dimethoxybenzopentathiepin and 6-(2-aminoethyl)benzopentathiepin, which are partial structures of varacin, were synthesized from 1,2-dimethoxybenzene and 1,2-benzenedithiol respectively.

Dinuclear complexes with bis (benzenedithiolate) ligands

As a part of a broader study directed towards helical coordination compounds with benzenedithiolate donors, we have synthesized the bis(benzenedithiol) ligands 1,2-bis(2,3-dimercaptobenzamido)ethane (H4-1) and 1,2-bis(2,3-dimercaptophenyl)ethan

ortho-lithiation of benzene-1,2-dithiol: A methodology for ortho-functionalization of benzene-1,2-dithiol

The ortho-lithiation of benzene-1,2-dithiol with three equivalents of nBuLi afforded monoas well as di-C-lithiated intermediates. The surprising kinetically controlled formation of di-C-lithiated species offers the opportunity to obtain dimercaptobenzoic and -terephthalic acid derivatives in a onepot synthesis in reasonable yields. Both compounds are versatile building blocks for the synthesis of macrocycles containing arylenedithiol units. Focusing on novel terephthalic acid derivatives, two preparation routes, via amide and via alkyl linkage, respectively, have been elaborated. The reaction sequence (i) sulfur protection using either isopropyl or benzyl groups, (ii) transformation of the carboxylic function into an amide or an alkyl group and (iii) subsequent removal of the protection groups afforded the terephthaldiamidedithiol 6 and the 1,2-bis(2,3-dimercaptophenyl)ethane 11.

Synthesis and characterization of functionalized benzopentathiepins

Four benzopentathiepins (12, 14, 16, and 18) having a functional group, such as aminoethyl, pyridyl, pyrimidinyl, and thienyl groups, respectively, on the benzene ring were synthesized from 3-substituted 1,2-benzenedithiol by sulfurization with elemental