165330-28-9

Upstream product

• 7149-58-8 diethoxyacetic acid piperidinyl amide 
• 120506-39-0 (4-(bromomethyl)phenoxy) (tert-butyl) dimethylsilane 
• 123-08-0 4-hydroxy-benzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 138585-08-7 (4-((tert-butyldimethylsilyl)oxy)phenyl)methanol 
• 120743-99-9 p-[(tert-butyldimethylsilyl)oxy]benzaldehyde 
• 6065-82-3 Ethyl diethoxyacetate 
• 138585-09-8 4-(tert-butyldimethylsilyloxy)benzyl chloride 

Downstream Products

• 10589-27-2 3-(p-hydroxyphenyl)-2-oxopropanal 
• 55779-48-1 coelenterazine 
• 1338220-09-9 (E)-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-styrylimidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-11-3 2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-(naphthalen-1-yl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-13-5 2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-(naphthalen-2-yl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-17-9 2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)-8-(thiophen-3-yl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-19-1 8-(benzo[b]thiophen-2-yl)-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one 
• 1338220-21-5 8-(benzo[b]thiophen-3-yl)-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one 

Relevant academic research and scientific papers

FLUOROCHROME-COUPLED COELENTERAZINE

PROBLEM TO BE SOLVED: To provide techniques of making the light emission wavelength of a Renilla luciferase (Rluc)-coelenterazine light-emitting system longer by modifying coelenterazine. SOLUTION: A fluorochrome-coupled coelenterazine is represented by t

Coelenterazine analog and preparing method and application thereof

The invention discloses a coelenterazine analog and a preparing method and application thereof. The coelenterazine analog has the general structure formula (I) shown in the description, wherein R1, R2 and R3 in the formula are different substituents. According to application of the compound as a bioluminescence substrate, the existence and quantity (including the enzyme level, the cell level and the animal level) of coelenterazine luciferase can be detected with bioluminescence, and the in vitro, cell and in vivo distribution imaging of luciferase can be detected; the compound can serve as a report signal to detect the pharmacologic action and the toxic effect of medicine on the enzyme level, the cell level and the animal level under the existence of luciferase.

Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution

Three novel coelenterazine (CTZ) derivatives with extension at the C-6 position of the imidazopyrazinone structure show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop CTZ derivatives w

COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES

Coelenterazine analogs with different luminescence properties from conventional ones and coelenteramide analogs with different fluorescence properties from conventional ones have been desired. The invention provides coelenterazine analogs modified at the

COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES

Coelenterazine analogues with different luminescence properties from conventional ones and coelenteramide analogues with different fluorescence properties from conventional ones have been desired. The invention provides coelenterazine analogues modified at the 8-position of coelenterazine and coelenteramide analogues modified at the 2- or 3-position of coelenteramide.

Chemi- and bioluminescence of coelenterazine analogues possessing an adamantylmethyl group

Coelenterazine analogues possessing the adamantylmethyl group at the C2 or C8 position were prepared to study their effects on chemi- and bioluminescence. Stability of the excited state coelenteramide analogues was significantly affected by the substituti