16552-49-1

Basic information

• Product Name: (4-METHOXY-PHENYL)-PYRIDIN-4-YLMETHYL-AMINE
• Synonyms: (4-METHOXY-PHENYL)-PYRIDIN-4-YLMETHYL-AMINE;TIMTEC-BB SBB011294
• CAS NO: 16552-49-1
• Molecular Formula: C₁₃H₁₄N₂O
• Molecular Weight: 214.26
• Mol File: 16552-49-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-METHOXY-PHENYL)-PYRIDIN-4-YLMETHYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-METHOXY-PHENYL)-PYRIDIN-4-YLMETHYL-AMINE(16552-49-1)
• EPA Substance Registry System: (4-METHOXY-PHENYL)-PYRIDIN-4-YLMETHYL-AMINE(16552-49-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 16552-49-1(Hazardous Substances Data)

Usage

General Description

The chemical (4-Methoxy-phenyl)-pyridin-4-ylmethyl-amine, also known as 4-methoxyphenylpyridin-4-ylmethylamine, is a compound with the molecular formula C13H14N2O. It belongs to the class of organic compounds known as anilines, which are aromatic amines derived from benzene. This particular compound contains a pyridine ring and a methoxyphenyl group. It has potential applications in pharmaceuticals and organic synthesis due to its structural features, which may contribute to its interaction with biological systems. The compound's properties and potential uses could make it of interest to researchers in medicinal chemistry and drug development.

Upstream product

• 27060-33-9 thioisonicotinic acid p-anisidide 
• 129985-68-8 N-(4-methoxyphenyl)-1-(pyridin-4-yl)methanimine 
• 3731-53-1 4-(aminomethyl)pyridine 
• 100-66-3 methoxybenzene 
• 872-85-5 pyridine-4-carbaldehyde 
• 100-17-4 para-methoxynitrobenzene 
• 7216-42-4 isonicotinaldehyde 1-oxide 
• 104-94-9 4-methoxy-aniline 
• 1822-51-1 4-picolylchloride hydrochloride 

Downstream Products

• 1018075-52-9 C₁₆H₁₈N₂O 

Relevant articles and documents

Reductive Amination Revisited: Reduction of Aldimines with Trichlorosilane Catalyzed by Dimethylformamide─Functional Group Tolerance, Scope, and Limitations

Aldimines, generated in situ from aliphatic, aromatic, and heteroaromatic aldehydes and aliphatic, aromatic, and heteroaromatic primary or secondary amines, can be reduced with trichlorosilane in the presence of dimethylformamide (DMF) as an organocatalys

Expedient Synthesis of N-Methyl- and N-Alkylamines by Reductive Amination using Reusable Cobalt Oxide Nanoparticles

N-Methyl- and N-alkylamines represent important fine and bulk chemicals that are extensively used in both academic research and industrial production. Notably, these structural motifs are found in a large number of life-science molecules and play vital roles in regulating their activities. Therefore, the development of convenient and cost-effective methods for the synthesis and functionalization of amines by using earth-abundant metal-based catalysts is of scientific interest. In this regard, herein we report an expedient reductive amination process for the selective synthesis of N-methylated and N-alkylated amines by using nitrogen-doped, graphene-activated nanoscale Co3O4-based catalysts. Starting from inexpensive and easily accessible nitroarenes or amines and aqueous formaldehyde or aldehydes in the presence of formic acid, this cost-efficient reductive amination protocol allows the synthesis of various N-methyl- and N-alkylamines, amino acid derivatives, and existing drug molecules.

Cyclobutadiene Metal Complexes: A New Class of Highly Selective Catalysts. An Application to Direct Reductive Amination

A catalyst of a new type, cyclobutadiene complex [(C4Et4)Rh(p-xylene)]PF6, was found to promote selective reductive amination in the presence of carbon monoxide under mild conditions (1-3 bar, 90 °C). The reaction demonstr